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Gene transfer and the ethics of first-in-human research : lost in translation /
"Human gene transfer is widely regarded as one of the most promising technologies for the treatment of a variety of disorders, but it presents practitioners with a variety of difficult ethical questions. Gene Transfer and the Ethics of First-in-Human Research examines the ethical and policy dim...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cambridge, UK ; New York :
Cambridge University Press,
2010.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 100 | 1 | |a Kimmelman, Jonathan. | |
| 245 | 1 | 0 | |a Gene transfer and the ethics of first-in-human research : |b lost in translation / |c Jonathan Kimmelman. |
| 260 | |a Cambridge, UK ; |a New York : |b Cambridge University Press, |c 2010. | ||
| 300 | |a 1 online resource (xi, 205 pages) | ||
| 336 | |a text |b txt |2 rdacontent | ||
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| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a "Human gene transfer is widely regarded as one of the most promising technologies for the treatment of a variety of disorders, but it presents practitioners with a variety of difficult ethical questions. Gene Transfer and the Ethics of First-in-Human Research examines the ethical and policy dimensions of testing interventions in human beings for the first time. The book discusses the difficult ethical challenges that arise from attempting to translate laboratory discoveries into clinical applications. These range from which available techniques to use, when to initiate human testing, questions of consent, expectation in public arenas, how to define acceptable risk, and the inclusion of vulnerable or disadvantaged subjects in early phase trials. This book is relevant to ethicists, legal practitioners, policy makers, geneticists and clinicians involved in clinical trials of new medical interventions"--Provided by publisher. | ||
| 505 | 0 | |a Introduction: gene transfer lost in translation -- What is gene transfer? -- Safety, values, and legitimacy: the protean nature of risk in translational trials -- Taming uncertainty: risk and gene-transfer clinical research -- Succor or suckers? Benefit, risk, and the therapeutic misconception -- Looking backward: a model value for translational trials -- The chasm: the ethics of initiating first-in-human clinical trials -- Tropic of cancers: gene transfer in resource-poor settings -- Great expectations and hard times: expectation management in gene transfer -- Something in the sight adjusts itself: conclusions. | |
| 588 | 0 | |a Print version record. | |
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Gene therapy |x Moral and ethical aspects. | |
| 650 | 0 | |a Clinical trials |x Moral and ethical aspects. | |
| 650 | 1 | 2 | |a Gene Transfer Techniques |x ethics |
| 650 | 2 | 2 | |a Human Experimentation |x ethics |
| 650 | 2 | 2 | |a Public Policy |
| 650 | 6 | |a Thérapie génique |x Aspect moral. | |
| 650 | 6 | |a Études cliniques |x Aspect moral. | |
| 650 | 7 | |a PSYCHOLOGY |x Psychotherapy |x General. |2 bisacsh | |
| 650 | 7 | |a Clinical trials |x Moral and ethical aspects |2 fast | |
| 650 | 7 | |a Gene therapy |x Moral and ethical aspects |2 fast | |
| 758 | |i has work: |a Gene transfer and the ethics of first-in-human research (Text) |1 https://id.oclc.org/worldcat/entity/E39PCFBktfXKdB6kh94WYPPQD3 |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Kimmelman, Jonathan. |t Gene transfer and the ethics of first-in-human research. |d Cambridge, UK ; New York : Cambridge University Press, 2010 |z 9780521690843 |w (DLC) 2009029830 |w (OCoLC)428770843 |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=3004564 |z Texto completo |
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