Information Processing by Biochemical Systems : Neural Network-Type Configurations /
Describes fully delineated biochemical systems, organized as neural network-type assemblies. It explains the relationship between these two apparently unrelated fields, revealing how biochemical systems have the advantage of using the "language" of the physiological processes and, therefor...
Clasificación: | Libro Electrónico |
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Autor principal: | |
Otros Autores: | |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Hoboken, N.J. :
John Wiley & Sons,
©2010.
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Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Cover
- Title Page
- Copyright Page
- Table of Contents
- Preface
- Terminology
- List of Symbols and Acronyms
- 1 Introduction and Literature Survey
- 1.1 Introduction
- 1.2 Computational Processes Based on Biological Principles
- 1.2.1 Modeling Biological Processes
- 1.2.2 Artificial Neural Networks
- 1.3 Molecular and Biomolecular Electronics
- 1.3.1 Motivation
- 1.3.2 Molecular Electronics
- 1.3.3 Biomolecular Electronics
- 1.4 Biochemical Devices Based on Enzymic Reactions
- 1.5 Oscillations in Biochemical Systems
- 1.6 Kinetic Characteristics of Cyclic Enzyme Systems
- 2 Background and Goals of This Study
- 3 Materials and Methods
- 3.1 Materials
- 3.2 Instruments
- 3.3 Experimental Methods
- 3.3.1 Determination of Kinetic Constants
- 3.3.2 Determination of the Inhibition Constant for Inhibition of Glutathione Reductase by Glucose-6-Phosphate
- 3.3.3 Immobilization on Affi-Gel 10
- 3.3.4 Assay for Glucose-6-Phosphate Dehydrogenase
- 3.3.5 Assay for Glutathione Reductase
- 3.4 Computational Methods
- 4 Results
- 4.1 The Basic System: Theoretical Considerations and Results
- 4.1.1 Characteristics of the Basic System
- 4.1.2 The Basic System as an Information-Processing Unit
- 4.1.3 Analytical Models for the Basic System
- 4.1.4 Results of Numerical Simulations for the Basic System
- 4.2 Neural Network8230;Type Biochemical Systems for Information Processing
- 4.2.1 Network A
- 4.2.2 Network B
- 4.2.3 Network C
- 4.3 The Basic System: Experimental Results
- 4.3.1 Deciding on the Experimental System
- 4.3.2 Kinetic Study of the Experimental System
- 4.3.3 Control of the Input Signal
- 4.3.4 The Basic System in a Fed-Batch Reactor
- 4.3.5 Internal Inhibition in the Basic System
- 4.3.6 Prediction of the Analytical Model Considering Internal Inhibition in a Fed-Batch Reactor
- 4.3.7 Immobilization of G6PDH and GR
- 4.3.8 The Basic System in a Packed Bed Reactor
- 4.4 The Extended Basic System: Theoretical Considerations and Results
- 4.4.1 Characteristics of the Extended Basic System
- 4.4.2 The Extended Basic System as an Information-Processing Unit
- 4.4.3 Analytical Model for the Extended Basic System
- 4.4.4 Results of Numerical Simulations for the Extended Basic System
- 5 Discussion
- 5.1 The Basic System
- 5.1.1 Fed-Batch Reactor: Numerical Simulations
- 5.1.2 Continuous Reactor: Numerical Simulations
- 5.1.3 Assessment of Experimental Results
- 5.2 The Extended Basic System
- 5.3 Biochemical Networks
- 5.4 Comparing Artificial Neural Networks with Biochemical Networks
- 5.5 Comparing Biochemical Networks to Computational Models
- 6 Conclusions
- References
- Index.