Targeting protein kinases for cancer therapy /

An expert guide to targeting protein kinases in cancer therapy. Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharma-ceutical scientists have targeted kinases for intensive study, and hav...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Matthews, David J. (David John), 1965-
Otros Autores: Gerritsen, Mary E.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, N.J. : Wiley, ©2010.
Temas:
Protein kinases > Inhibitors > Therapeutic use.
Antineoplastic agents.
Protein kinases.
Drug resistance in cancer cells.
Neoplasms > drug therapy
Protein Kinase Inhibitors > therapeutic use
Drug Discovery
Drug Resistance, Neoplasm
Protein Kinases > physiology
Protein-Tyrosine Kinases > antagonists & inhibitors
Protein Kinases
Anticancéreux.
Protéines kinases.
Cellules cancéreuses > Résistance aux médicaments.
MEDICAL > Pharmacology.
Drug resistance in cancer cells
Antineoplastic agents
Protein kinases
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Kinases and cancer
  • Protein kinase structure, function, and regulation
  • Receptor tyrosine kinases
  • Nonreceptor tyrosine kinases
  • Intracellular signal transduction cascades
  • Cell cycle control
  • Structural biochemistry of kinase inhibitors
  • Tyrosine kinase inhibitors
  • Angiokinase inhibitors
  • Intracellular signaling kinase inhibitors
  • Current challenges and future directions.

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