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|a 10.1002/9780470555293
|b Wiley InterScience
|n http://www3.interscience.wiley.com
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|a Matthews, David J.
|q (David John),
|d 1965-
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|a Targeting protein kinases for cancer therapy /
|c David J. Matthews, Mary E. Gerritsen.
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260 |
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|a Hoboken, N.J. :
|b Wiley,
|c ©2010.
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300 |
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|a 1 online resource (xiii, 702 pages) :
|b illustrations (chiefly color)
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336 |
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|a text
|b txt
|2 rdacontent
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|b c
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|a Includes bibliographical references and index.
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|a Kinases and cancer -- Protein kinase structure, function, and regulation -- Receptor tyrosine kinases -- Nonreceptor tyrosine kinases -- Intracellular signal transduction cascades -- Cell cycle control -- Structural biochemistry of kinase inhibitors -- Tyrosine kinase inhibitors -- Angiokinase inhibitors -- Intracellular signaling kinase inhibitors -- Current challenges and future directions.
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|a An expert guide to targeting protein kinases in cancer therapy. Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharma-ceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication. Complete with full-color presentations, Targeting Protein Kinases for Cancer Therapydefines the structural features of protein kinases and examines their cellular func-tions. Combining kinase biology with.
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|a Print version record.
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546 |
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|a English.
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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|a Protein kinases
|x Inhibitors
|x Therapeutic use.
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|a Antineoplastic agents.
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|a Protein kinases.
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|a Drug resistance in cancer cells.
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|a Neoplasms
|x drug therapy
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|a Protein Kinase Inhibitors
|x therapeutic use
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|a Drug Discovery
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|a Drug Resistance, Neoplasm
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|a Protein Kinases
|x physiology
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|a Protein-Tyrosine Kinases
|x antagonists & inhibitors
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|a Protein Kinases
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|a Anticancéreux.
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|a Protéines kinases.
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|a Cellules cancéreuses
|x Résistance aux médicaments.
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|a MEDICAL
|x Pharmacology.
|2 bisacsh
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|a Drug resistance in cancer cells
|2 fast
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|a Antineoplastic agents
|2 fast
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|a Protein kinases
|2 fast
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|a Gerritsen, Mary E.
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|i has work:
|a Targeting protein kinases for cancer therapy (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCFHmbYtv8hrYd4Q33GQFVd
|4 https://id.oclc.org/worldcat/ontology/hasWork
|
776 |
0 |
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|i Print version:
|a Matthews, David J. (David John), 1965-
|t Targeting protein kinases for cancer therapy.
|d Hoboken, N.J. : John Wiley & Sons, ©2010
|z 9780470229651
|w (DLC) 2009020804
|w (OCoLC)338289165
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