Enantioselective synthesis of [beta]-amino acids /
Covers all facets of the synthesis of ?-amino acidsAs evidenced by an exponential increase in the literature published on the subject, interest in ?-amino acids has grown over the past several years. With major pharmaceutical applications, these amino acids are now studied across multiple lines of r...
Clasificación: | Libro Electrónico |
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Otros Autores: | , |
Formato: | Electrónico eBook |
Idioma: | Inglés |
Publicado: |
Hoboken, N.J. :
Wiley,
©2005.
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Edición: | 2nd ed. |
Temas: | |
Acceso en línea: | Texto completo |
Tabla de Contenidos:
- ENANTIOSELECTIVE SYNTHESIS OF b-AMINO ACIDS; CONTENTS; Preface; Preface to the First Edition; Contributors; 1. Structural Types of Relevant b-Amino Acid Targets; 2. b-Amino Acids in Natural Products; 3. Preparation of Enantiopure b-Amino Acids by Homologation of a-Amino Acids; 4. Asymmetric Catalysis in Enantioselective Synthesis of b-Amino Acids; 5. Enantioselective Synthesis of Conformationally Constrained b-Amino Acids; 6. Catalytic Enantioselective Mannich Reactions; 7. Enantioselective Synthesis of b-Amino Acids via Stereoselective Hydrogenation of b-Aminoacrylic Acid Derivatives
- 8. Asymmetric Synthesis of b-Amino Acids by Enolate Additions to tert-Butanesulfinyl Imines9. Organocatalytic Approaches to Enantioenriched b-Amino Acids; 10. Asymmetric Synthesis of Cyclic b-Amino Acids via Cycloaddition Reactions; 11. Enantioselective Synthesis of Novel b-Amino Acids; 12. Asymmetric Synthesis of Phosphonic Analogs of b-Amino Acids; 13. Asymmetric Synthesis of a-Substituted-b-Amino Phosphonates and Phosphinates and b-Amino Sulfur Analogs; 14. Stereoselective Synthesis of Fluorine-Containing b-Amino Acids
- 15. Enantioselective Synthesis of b-Amino Acids via Conjugate Addition to a,b-Unsaturated Carbonyl Compounds16. Preparation of Enantiopure b-Amino Acids via Enantioselective Conjugate Addition; 17. Biocatalytic Entry to Enantiomerically Pure b-Amino Acids; 18. Stereoselective Synthesis of b-Amino Acids via Radical Reactions; 19. Recent Advances in Synthesis of a-Hydroxy-b-amino Acids and Their Use in SAR Studies of Taxane Anticancer Agents; 20. Synthesis of b-Amino Acids and Their Derivatives from b-Lactams: Update
- 21. Multiple-Component Condensation Methods for Preparation of Combinatorial Libraries of b-Amino Carbonyl Derivatives22. Using Constrained b-Amino Acid Residues to Control b-Peptide Shape and Function; 23. b(2)-Amino Acids with Proteinogenic Side Chains and Corresponding Peptides: Synthesis, Secondary Structure, and Biological Activity; Index