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G-protein coupled receptors : methods express /

G-Protein Coupled Receptors (GPCRs) are not only the largest protein family in the human genome but are also the single biggest target for therapeutic agents. Research into GPCRs is therefore growing at a fast pace and the range of techniques that can be applied to GPCRs is vast and continues to gro...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Poyner, David, Wheatley, Mark, Dr
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Chichester, West Sussex, UK ; Hoboken, NJ : John Wiley & Sons, 2010.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • G Protein-Coupled Receptors; Contents; Preface; Contributors; 1 Measurement of Ligand-G Protein-coupled Receptor Interactions; 2 Second Messenger Assays for G Protein-coupled Receptors: cAMP, Ca2+, Inositol Phosphates, ERK1/2; 3 Use of the [35S]GTP?S Binding Assay to Determine Ligand Efficacy at G Protein-coupled Receptors; 4 Quantitative Imaging of Receptor Trafficking; 5 Production of Recombinant G Protein-coupled Receptor in Yeast for Structural and Functional Analysis; 6 Monitoring GPCR-Protein Complexes Using Bioluminescence Resonance Energy Transfer.