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|a 10.1002/9780470682920
|b Wiley InterScience
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|a UAMI
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100 |
1 |
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|a Kelly, John,
|d 1961-
|1 https://id.oclc.org/worldcat/entity/E39PCjJx9fCV3K7VvvFvyT3xXd
|
245 |
1 |
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|a Principles of CNS drug development :
|b from test tube to patient /
|c John Kelly.
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246 |
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|a Principles of central nervous system drug development :
|b from test tube to patient
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|a Chichester, UK ;
|a Hoboken, NJ :
|b Wiley-Blackwell,
|c ©2009.
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300 |
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|a 1 online resource (xx, 304 pages) :
|b illustrations
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336 |
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|a text
|b txt
|2 rdacontent
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|a Includes bibliographical references and index.
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|a An overview of the major CNS disorders -- Neurobiological correlates of CNS disorders -- Current pharmacological targets -- Premarketing efficacy evaluation -- Pharmacokinetic considerations : absorption, distribution, metabolism, and elimination -- Safety concerns relating to CNS drugs -- Preclinical and clinical safety evaluation -- CNS drug targets in development and future perspectives.
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|a This title acts as a primer, giving students and newcomers to the field an opportunity to learn about the breadth of the CNS drug discovery and the various stages in the drug discovery process-from evaluating drugs for their efficacy and safety in animals and humans to identifying future drug targets. The content of the book is heavily informed by recent experimental evidence and the impediments in the pipeline of drug discovery. It draws on the attempts to develop translational research strategies in CNS drug development. The title highlights the emergence of a "critical path" for the develop
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|a Print version record.
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
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|a Neuropharmacology.
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650 |
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|a Drug development.
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650 |
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2 |
|a Central Nervous System Agents
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650 |
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|a Neuropharmacology
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|a Central Nervous System Diseases
|x drug therapy
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|a Drug Discovery
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650 |
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|a Neuropharmacologie.
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650 |
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|a Médicaments
|x Développement.
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650 |
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|a Médicaments du système nerveux central.
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|a MEDICAL
|x Pain Medicine.
|2 bisacsh
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|a MEDICAL
|x Psychiatry
|x Psychopharmacology.
|2 bisacsh
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650 |
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|a Drug development
|2 fast
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|a Neuropharmacology
|2 fast
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758 |
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|i has work:
|a Principles of CNS drug development (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCFPxKbqHHdWcR4tcWpHJrC
|4 https://id.oclc.org/worldcat/ontology/hasWork
|
776 |
0 |
8 |
|i Print version:
|a Kelly, John, 1961-
|t Principles of CNS drug development.
|d Chichester, UK ; Hoboken, NJ : Wiley-Blackwell, 2009
|z 9780470519790
|w (DLC) 2009041400
|w (OCoLC)456641908
|
856 |
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|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=470600
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