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Pharmacogenetics of Breast Cancer : Towards the Individualization of Therapy.

Pharmacogenetics, generally referred to as the study of genetic variation that gives rise to differing response to drugs, is becoming more relevant in the diagnosis, treatment, and recovery of cancer patients. The problem faced when treating cancer is the outstanding varied efficacy between success...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Leyland-Jones, Brian
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Informa Healthcare, 2008.
Colección:Translational Medicine, 7.
Temas:
Acceso en línea:Texto completo

MARC

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049 |a UAMI 
100 1 |a Leyland-Jones, Brian. 
245 1 0 |a Pharmacogenetics of Breast Cancer :  |b Towards the Individualization of Therapy. 
260 |a New York :  |b Informa Healthcare,  |c 2008. 
300 |a 1 online resource (352 pages). 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Translational Medicine, 7 
520 |a Pharmacogenetics, generally referred to as the study of genetic variation that gives rise to differing response to drugs, is becoming more relevant in the diagnosis, treatment, and recovery of cancer patients. The problem faced when treating cancer is the outstanding varied efficacy between success and failure. Unpredictability between a population of patients who are affected with the same occurring malignancy can show varying associated toxicities in drug treatment ranging from zero effect through lethal doses. Since the chemotherapeutic agent is often developed to fit the average patient th. 
588 0 |a Print version record. 
505 0 |a ""Preface""; ""Acknowledgments""; ""Contents""; ""Contributors""; ""1 Pharmacogenetics of Breast Cancer: Toward the Individualization of Therapy""; ""2 Pharmacology, Pharmacogenetics, and Pharmacoepidemiology: Three Pâ€?s of Individualized Therapy""; ""3 Role of Genetic Variability in Breast Cancer Treatment Outcomes""; ""4 The Role of Epigenetics in Breast Cancer: Implications for Diagnosis, Prognosis, and Treatment""; ""5 Comparative Genomic Hybridization and Copy Number Abnormalities in Breast Cancer"" 
505 8 |a ""6 Gene Expression Profiling as an Emerging Diagnostic Tool to Personalize Chemotherapy Selection for Early Stage Breast Cancer""""7 Gene Expressionâ€?Based Predictors of Prognosis and Response to Chemotherapy in Breast Cancer""; ""8 Utilization of Genomic Signatures for Personalized Treatment of Breast Cancer""; ""9 Personalized Medicine by the Use of Microarray Gene Expression Profiling""; ""10 Predictive Markers for Targeted Breast Cancer Treatment""; ""11 Circulating Tumor Cells in Individualizing Breast Cancer Therapy""; ""12 Individualization of Endocrine Therapy in Breast Cancer"" 
505 8 |a ""13 TAILORx: Rationale for the Study Design""""14 Taking Prognostic Signatures to the Clinic""; ""15 Tissue is the Issue""; ""16 Acquisition and Preservation of Tissue for Microarray Analysis""; ""17 Tapping into the Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Gold Mine for Individualization of Breast Cancer Treatment""; ""18 Breast Cancer Stem Cells and Their Niche: Lethal Seeds in Lethal Soil""; ""19 Molecular Imaging in Individualized Cancer Management""; ""20 Cancer Nanotechnology for Molecular Profiling and Individualized Therapy""; ""Index"" 
504 |a Includes bibliographical references and index. 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Breast  |x Cancer  |x Genetic aspects. 
650 0 |a Breast  |x Cancer  |x Chemotherapy. 
650 0 |a Pharmacogenetics. 
650 1 2 |a Breast Neoplasms  |x genetics 
650 2 2 |a Breast Neoplasms  |x drug therapy 
650 2 |a Pharmacogenetics 
650 6 |a Sein  |x Cancer  |x Aspect génétique. 
650 6 |a Sein  |x Cancer  |x Chimiothérapie. 
650 6 |a Pharmacogénétique. 
650 7 |a MEDICAL  |x Oncology.  |2 bisacsh 
650 7 |a HEALTH & FITNESS  |x Diseases  |x Cancer.  |2 bisacsh 
650 7 |a Breast  |x Cancer  |x Chemotherapy  |2 fast 
650 7 |a Breast  |x Cancer  |x Genetic aspects  |2 fast 
650 7 |a Pharmacogenetics  |2 fast 
776 1 |z 9781420052930 
830 0 |a Translational Medicine, 7. 
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