Cargando…

Vascular complications of diabetes : current issues in pathogenesis and treatment /

Diabetes has reached epidemic proportions, and the cardiovascular complications of diabetes are life-threatening and disabling. This book is unique in providing a simple explanation of the biochemical role of PKC in diabetes complications, which allows clinicians to understand why PKC inhibitors (in...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Donnelly, Richard, 1960- (Editor ), Horton, Edward S. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Chichester : John Wiley & Sons, 2007.
Edición:2nd ed.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • The public health impact of the diabetes epidemic
  • Risk factors
  • Diabetic nephropathy
  • Coronary heart disease and diabetes
  • Diabetes and cerebrovascular disease
  • Erectile dysfunction
  • Evidence-based interventions to prevent or retard vascular complications
  • Classification and clinical features of neuropathy
  • Pathophysiology of diabetic neuropathy
  • Epidemiology and natural history of DPN
  • Detection/screening/assessment
  • Foot ulceration and Charcot arthropathy
  • Treatment options
  • Management guidelines for diabetic peripheral neuropathy and foot ulceration
  • Diabetic retinopathy : epidemiology and risk factors
  • Classification and diagnosis of diabetic retinopathy
  • Diabetic maculopathy
  • Proliferative diabetic retinopathy
  • Non-retinal diabetic ocular complications
  • Pathophysiology and potential targets for therapeutic intervention
  • Protein kinase C
  • PKC activation and vascular permeability
  • Role of protein kinase C activation in cardiovascular and renal complications of diabetes
  • Experimental pharmacology using isoform-selective protein kinase C inhibitors
  • Clinical trials with ruboxistaurin.