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Vascular complications of diabetes : current issues in pathogenesis and treatment /
Diabetes has reached epidemic proportions, and the cardiovascular complications of diabetes are life-threatening and disabling. This book is unique in providing a simple explanation of the biochemical role of PKC in diabetes complications, which allows clinicians to understand why PKC inhibitors (in...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Chichester :
John Wiley & Sons,
2007.
|
| Edición: | 2nd ed. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 001 | EBOOKCENTRAL_ocn476173140 | ||
| 003 | OCoLC | ||
| 005 | 20240329122006.0 | ||
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| 066 | |c (S | ||
| 019 | |a 437218859 | ||
| 020 | |a 9780470751497 |q (electronic bk.) | ||
| 020 | |a 0470751495 |q (electronic bk.) | ||
| 029 | 1 | |a DEBBG |b BV044130198 | |
| 035 | |a (OCoLC)476173140 |z (OCoLC)437218859 | ||
| 050 | 4 | |a RC700.D5 V |a RC700.D5V375 2005 | |
| 082 | 0 | 4 | |a 616.13 |
| 049 | |a UAMI | ||
| 245 | 0 | 0 | |a Vascular complications of diabetes : |b current issues in pathogenesis and treatment / |c editor, Richard Donnelly ; associate editor, Edward Horton. |
| 250 | |a 2nd ed. | ||
| 260 | |a Chichester : |b John Wiley & Sons, |c 2007. | ||
| 300 | |a 1 online resource (242 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a The public health impact of the diabetes epidemic -- Risk factors -- Diabetic nephropathy -- Coronary heart disease and diabetes -- Diabetes and cerebrovascular disease -- Erectile dysfunction -- Evidence-based interventions to prevent or retard vascular complications -- Classification and clinical features of neuropathy -- Pathophysiology of diabetic neuropathy -- Epidemiology and natural history of DPN -- Detection/screening/assessment -- Foot ulceration and Charcot arthropathy -- Treatment options -- Management guidelines for diabetic peripheral neuropathy and foot ulceration -- Diabetic retinopathy : epidemiology and risk factors -- Classification and diagnosis of diabetic retinopathy -- Diabetic maculopathy -- Proliferative diabetic retinopathy -- Non-retinal diabetic ocular complications -- Pathophysiology and potential targets for therapeutic intervention -- Protein kinase C -- PKC activation and vascular permeability -- Role of protein kinase C activation in cardiovascular and renal complications of diabetes -- Experimental pharmacology using isoform-selective protein kinase C inhibitors -- Clinical trials with ruboxistaurin. | |
| 588 | 0 | |a Print version record. | |
| 520 | |a Diabetes has reached epidemic proportions, and the cardiovascular complications of diabetes are life-threatening and disabling. This book is unique in providing a simple explanation of the biochemical role of PKC in diabetes complications, which allows clinicians to understand why PKC inhibitors (in development) are an exciting prospect for future treatment to slow progression of eye & foot complications. New features of this Second Edition include :.:.; Updated throughout to reflect the impact of recent major clinical trials on current clinical practice.; Includes a major new section on diabe. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Diabetes |x Complications. | |
| 650 | 0 | |a Diabetic angiopathies. | |
| 650 | 0 | |a Diabetic retinopathy. | |
| 650 | 0 | |a Protein kinase C. | |
| 650 | 0 | |a Medicine. | |
| 650 | 2 | |a Diabetes Complications | |
| 650 | 2 | |a Diabetic Angiopathies | |
| 650 | 2 | |a Diabetic Retinopathy | |
| 650 | 2 | |a Protein Kinase C | |
| 650 | 2 | |a Medicine | |
| 650 | 4 | |a Vascular Diseases. | |
| 650 | 4 | |a Diabetes Complications. | |
| 650 | 4 | |a Diabetic retinopathy. | |
| 650 | 4 | |a Protein Kinase C. | |
| 650 | 4 | |a Diabetic angiopathies. | |
| 650 | 6 | |a Diabète |x Complications et séquelles. | |
| 650 | 6 | |a Angiopathies diabétiques. | |
| 650 | 6 | |a Rétinopathie diabétique. | |
| 650 | 6 | |a Protéine kinase C. | |
| 650 | 6 | |a Médecine. | |
| 650 | 7 | |a medicines (material) |2 aat | |
| 650 | 7 | |a medicine (discipline) |2 aat | |
| 650 | 7 | |a Diabetes |x Complications |2 fast | |
| 650 | 7 | |a Diabetic angiopathies |2 fast | |
| 650 | 7 | |a Diabetic retinopathy |2 fast | |
| 650 | 7 | |a Medicine |2 fast | |
| 650 | 7 | |a Protein kinase C |2 fast | |
| 700 | 1 | |a Donnelly, Richard, |d 1960- |e editor. |1 https://id.oclc.org/worldcat/entity/E39PBJbtmDHQDGWCFF4jGfq4v3 | |
| 700 | 1 | |a Horton, Edward S., |e editor. | |
| 776 | 1 | |z 9781405127851 | |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=351646 |z Texto completo |
| 880 | |6 520-00/(S |a Diabetes-related cardiovascular complications often cause premature mortality, as well as disabilities such as blindness, foot ulceration and amputation. The health care and social care costs of managing these complications are enormous, but new treatments, devices and clinical management protocols are steadily improving the longer term outcomes for people with diabetes. This second edition has been revised and updated to reflect state of the art clinical practice. In particular, a new section on diabetic neuropathy covers important aspects of screening and detection, diagnosis and management. The book is aimed at healthcare professionals involved in the assessment and surveillance of patients with diabetes complications, and the section on protein kinase C (PKC) explains the basis of a major new pathway responsible for hyperglycaemia-induced vascular injury. Recent clinical trials have suggested that inhibition of PKC-β is an effective therapeutic intervention for improving the symptoms and outcomes from diabetes-related complications. | ||
| 938 | |a 123Library |b 123L |n 3746 | ||
| 938 | |a ProQuest Ebook Central |b EBLB |n EBL351646 | ||
| 994 | |a 92 |b IZTAP | ||