Ethical Challenges in Study Design and Informed Consent for Health Research in Resource-poor Settings.

This review considers ethical challenges to research design and informed consent in biomedical and behavioral studies conducted in resource-poor settings. A review of the literature explores relevant social, cultural, and ethical issues in the conduct of biomedical and social health research in deve...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Marshall, P. A.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Geneva : World Health Organization, 2007.
Temas:
Human experimentation in medicine > Moral and ethical aspects > Case studies.
Human experimentation in medicine > Moral and ethical aspects > Cross-cultural studies.
Human experimentation in medicine > Moral and ethical aspects.
Medicine > Research > Moral and ethical aspects > Case studies.
Medicine > Research > Moral and ethical aspects > Cross-cultural studies.
Medicine > Research > Moral and ethical aspects.
Expérimentation humaine en médecine > Aspect moral > Études de cas.
Expérimentation humaine en médecine > Aspect moral > Études transculturelles.
Expérimentation humaine en médecine > Aspect moral.
Médecine > Recherche > Aspect moral > Études de cas.
Médecine > Recherche > Aspect moral > Études transculturelles.
Médecine > Recherche > Aspect moral.
Human experimentation in medicine > Moral and ethical aspects
Medicine > Research > Moral and ethical aspects
Case studies
Cross-cultural studies
Acceso en línea:Texto completo
Tabla de Contenidos:
  • EXECUTIVE SUMMARY; 1. INTRODUCTION; 1.1 Ethical principles in scientific research; 1.2 Historical background: declarations, guidelines and policies; 1.3 Recent developments; 2. ETHICAL CHALLENGES IN RESEARCH DESIGN; 2.1 Cultural context; 2.2 Health disparities; 2.3 Strengthening the commitment to ethical conduct in research design; 2.4 Standard of care and access to fair benefits; 3. ETHICAL CONSIDERATIONS FOR INFORMED CONSENT; 3.1 The process of informed consent: cultural and social context; 3.2 Preparation and documentation of the consent form.
  • 4. CASE ANALYSIS: ETHICAL DILEMMAS IN HEALTH RESEARCH IN RESOURCE-POOR SETTINGSCase 1: Old problems but new challenges: ethics review and informed consent in a clinical trial for HIV/AIDS in China (Gail Henderson and Dongbao Yu); Case 2: Designing a group-based intervention to promote condom use in HIV serodiscordant couples in three countries: India, Thailand and Uganda (Janet W. McGrath, Moses Kamya, David D. Celentano, and Andrew Fullem); Case 3: Clinical trial of antimalarial drugs in Kenya (Duncan Ngare).
  • Case 4: The impact of community dynamics on conducting scientific research in sub-Saharan Africa (Clement A. Adebamowo)Case 5: Protecting confidentiality of participants in studies of behaviours that transmit HIV-1 in Russia (Robert Heimer and Olga Borodkina); Case 6: A study of low birth weight in Madhya Pradesh, India (Ayesha De Costa); Case 7: Evaluating the natural history of Plasmodium vivax infection in children in Papua New Guinea (Peter Zimmerman and John Taime).
  • Case 8: Phase III trial of antibiotics to reduce chorioamnionitis-related perinatal HIV transmission in Malawi (Irving Hoffman and Charles Mwansambo)Case 9: Ethical review of epidemiological health studies in Pakistan: responsibilities of researchers for medical care of participants (Asad J. Raja); Case 10: Research and employment opportunities in resource-poor settings (Jeannine Coreil and Gladys Mayard); 5. RECOMMENDATIONS; 5.1 Recommendations for good practice; 5.2 Recommendations for research on research ethics; REFERENCES.

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