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The Subthalamic Nucleus.

Part II starts with a systemic model of the basal ganglia to evaluate the position of the STN in the direct, indirect and hyperdirect pathways. A summary of in vitro studies is given, describing STN spontaneous activity as well as responses to depolarizing and hyperpolarizing inputs, and high freque...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Heida, T. (Autor), Marani, Enrico (Autor), Usunoff, K. G. (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Guildford : Boulder : Springer London NetLibrary, Inc. [distributor]
Colección:Advances in Anatomy, Embryology and Cell Biology, 199.
Temas:
Acceso en línea:Texto completo

MARC

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245 1 4 |a The Subthalamic Nucleus. 
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490 1 |a Advances in Anatomy, Embryology and Cell Biology, 199 ;  |v v. v. 199 
505 0 |a 1 Introduction; 2 The Basal Ganglia; 2.1 Pathways Within the Basal Ganglia; 2.2 Parkinson's Disease; 2.3 Deep Brain Stimulation; 3 STN Activity Recorded in Vitro: Brain Slices; 3.1 Spontaneous Activity; 3.2 Depolarizing and Hyperpolarizing Inputs; 3.3 Ionic Mechanisms of a Plateau Potential; 3.4 Synaptic Inputs; 3.5 High-Frequency Stimulation of STN Cells; 3.6 Intrinsic Versus Extrinsic Properties: Bursts; 4 STN Activity Recorded in Vitro: Dissociated Cell Cultures; 4.1 Experimental Set-up; 4.2 Spontaneous Activity; 4.3 Addition of Acetylcholine; 4.4 Electrical Stimulation. 
505 8 |a 5 STN Cell Models and Simulation of Neuronal Networks5.1 Otsuka's Model; 5.2 Terman and Rubin's Model; 5.3 Comparison of the Otsuka Model with the Terman/Rubin Model; 5.4 The Multi-compartment STN Model of Gillies and Willshaw; 5.5 Intra-nuclear Network Models; 5.6 Inter-nuclear Network Models; 6 Comparison of Part I and Part II; 6.1 Recurrent STN Axons; 6.2 Inter-neurons in the STN; 6.3 Fibre Tracts around and in the STN; 6.4 Ca 2+ Receptors; 6.5 Three-Dimensional Modelling; 6.6 Types of Projection Neurons; 6.7 Neurotransmitter Input Versus Receptors in the STN. 
505 8 |a 6.8 The Pedunculopontine Nucleus6.9 Nigro-subthalamic Connections; 6.10 Another Cortico-subthalamic Loop; 6.11 Nissl-Based Subdivision of the STN; Appendix 1 Model Parameter Values Otsuka et al. 2004; Appendix 2 Model Parameter Values Terman et al. 2002; Rubinand Terman (2004); References; Index. 
520 |a Part II starts with a systemic model of the basal ganglia to evaluate the position of the STN in the direct, indirect and hyperdirect pathways. A summary of in vitro studies is given, describing STN spontaneous activity as well as responses to depolarizing and hyperpolarizing inputs, and high frequency stimulation. STN bursting activity and the underlying ionic mechanisms are investigated. Deep brain stimulation used for symptomatic treatment of Parkinsona (TM)s disease is discussed in terms of the elements that are influenced and its hypothesized mechanisms. This part of the monograph pays at. 
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650 0 |a Subthalamus. 
650 0 |a Subthalamus  |x Cytology. 
650 0 |a Basal ganglia. 
650 0 |a Neural networks (Neurobiology) 
650 2 |a Basal Ganglia 
650 6 |a Subthalamus. 
650 6 |a Subthalamus  |x Cytologie. 
650 6 |a Noyaux gris centraux. 
650 6 |a Réseaux neuronaux (Neurobiologie) 
650 7 |a Basal ganglia  |2 fast 
650 7 |a Neural networks (Neurobiology)  |2 fast 
650 7 |a Subthalamus  |2 fast 
700 1 |a Marani, Enrico,  |e author. 
700 1 |a Usunoff, K. G.,  |e author. 
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776 0 8 |i Print version:  |a Heida, Tjitske.  |t Subthalamic Nucleus Part II : Modelling and Simulation of Activity.  |d Dordrecht : Springer, ©2008  |z 9783540794615 
830 0 |a Advances in Anatomy, Embryology and Cell Biology, 199. 
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