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Live variola virus : considerations for continuing research /

Smallpox was a devastating disease that decimated human populations for centuries, and its eradication in 1980 was a monumental achievement for the global health community. Since then the remaining known strains of its causative agent, variola virus, have been contained in two World Health Organizat...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: Institute of Medicine (U.S.). Committee on the Assessment of Future Scientific Needs for Live Variola Virus
Otros Autores: Arvin, Ann M., Patel, Deepali
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Washington, D.C. : National Academies Press, ©2009.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Live variola virus :  |b considerations for continuing research /  |c Committee on the Assessment of Future Scientific Needs for Live Variola Virus, Board on Global Health ; Ann M. Arvin and Deepali M. Patel, editors ; Institute of Medicine of the National Academies. 
260 |a Washington, D.C. :  |b National Academies Press,  |c ©2009. 
300 |a 1 online resource (xvii, 151 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references. 
505 0 |a Introduction -- Overview of smallpox and its surveillance and control -- Comparative poxvirology -- Animal models using variola and other orthopoxvirses -- Genomic analysis -- Development of therapeutics -- Development of vaccines -- Methods for detection and diagnosis -- Discovery research -- Conclusions and recommendations. 
520 |a Smallpox was a devastating disease that decimated human populations for centuries, and its eradication in 1980 was a monumental achievement for the global health community. Since then the remaining known strains of its causative agent, variola virus, have been contained in two World Health Organization (WHO)-approved repositories. In 1999, the World Health Assembly (WHA) debated the issue of destroying these remaining strains. Arguments were presented on the need to retain the live virus for use in additional important research, and the decision to destroy the virus was deferred until this research could be completed. In that same year, the Institute of Medicine (IOM) convened a consensus committee to explore scientific needs for the live virus. In the ten years since the first IOM report, the scientific, political, and regulatory environments have changed. In this new climate, the IOM was once again tasked to consider scientific needs for live variola virus. The committee evaluated the scientific need for live variola virus in four areas: development of therapeutics, development of vaccines, genomic analysis, and discovery research. 
588 0 |a Print version record. 
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650 0 |a Smallpox  |x Research. 
650 0 |a Smallpox  |x Prevention. 
650 0 |a Smallpox vaccine. 
650 0 |a Virology  |x Cultures and culture media. 
650 0 |a Research. 
650 1 2 |a Variola virus 
650 2 |a Smallpox Vaccine 
650 2 |a Virus Cultivation 
650 2 2 |a Biomedical Research 
650 2 2 |a Research 
650 2 2 |a Smallpox 
650 2 2 |a Smallpox  |x prevention & control 
650 2 2 |a Smallpox  |x therapy 
650 6 |a Variole  |x Recherche. 
650 6 |a Variole  |x Prévention. 
650 6 |a Vaccin antivariolique. 
650 6 |a Virologie  |x Cultures et milieux de culture. 
650 6 |a Recherche. 
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650 7 |a Research  |2 fast 
650 7 |a Smallpox  |x Prevention  |2 fast 
650 7 |a Smallpox vaccine  |2 fast 
650 7 |a Virology  |x Cultures and culture media  |2 fast 
700 1 |a Arvin, Ann M. 
700 1 |a Patel, Deepali. 
710 2 |a Institute of Medicine (U.S.).  |b Committee on the Assessment of Future Scientific Needs for Live Variola Virus. 
758 |i has work:  |a Live variola virus (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCGdM9d3HG8Wf6KbCv6WYyd  |4 https://id.oclc.org/worldcat/ontology/hasWork 
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