Foundations of Comparative Genomics.

Mostrar otras versiones (2)

This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Mushegian, Arcady R.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Elsevier Science & Technology, 2007.
Temas:
Gene mapping.
Genomics.
Physiology, Comparative.
Cartes chromosomiques.
Génomique.
Physiologie comparée.
Gene mapping
Genomics
Physiology, Comparative
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover
  • Foundations of Comparative Genomics
  • Copyright Page
  • Contents
  • Dedication Page
  • Preface
  • Chapter 1: The Beginning of Computational Genomics
  • Chapter 2: Finding Sequence Similarities
  • Chapter 3: Homology: Can We Get It Right?
  • Glossary
  • Chapter 4: Getting Ready fot the Era of Comparative Genomics: The Importance of Viruses
  • Chapter 5: The First Fact of Comparative Genomics: Protein Sequences are Remarkably Resilient in Evolution
  • Chapter 6: The Second Fact of Comparative Genomics: Functional Convergence at the Molecular Level
  • Proteins with Same or Similar Functions
  • Proteins with Superficially Different Functions
  • Completely Uncharacterized Proteins
  • Analogous Function
  • Analogous Mechanism
  • Analogous Structure
  • Mechanisms of DOGs
  • DOGs and the Types of Homology
  • DOGs and Horizontal Gene Transfers
  • One-for-One and One-for-Many Relationships in DOGs
  • DOGs and Operons
  • DOGs and Gene Competition
  • DOGs, RNA-Protein Displacements, and RNA World
  • Detection of DOGs Using Phyletic Patterns and Phylogeny
  • Chapter 7: Prediction of Function and Reconstruction of Metabolism from Genomic Data: Homology-Based Approaches
  • Databases of Biochemical Information
  • Homology and Orthology: How to Use Them for Prediction of Protein Function, and What Can Go Wrong
  • Annotations by Homology and Errors Inherent in the Process
  • Placing Predicted Functions onto Metabolic Maps and Filling the Gaps
  • Chapter 8: Prediction of Function and Reconstruction of Metabolism: Post-Homology Approaches
  • Chapter 9: Structural Genomics:What Does It Tell Us about Life?
  • Chapter 10: How Many Protein Families are There?
  • Chapter 11: Phylogenetic Inference and the Era of Complete Genomes
  • Chapter 12: Two Stories about Evolution
  • Chapter 13: Minimal and Ancestral Genomes
  • Chapter 14: Comparative Genomics and Systems Biology
  • References
  • Index
  • Last Page.

Ejemplares similares