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Integrated cardiac safety : assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance /
The serious nature of cardiovascular adverse drug reactions occurring in patients makes assessment of a drug's cardiac safety profile a high priority during both development and post-approval monitoring. Integrated Cardiac Safety provides necessary guidance and methodology for professionals ass...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Hoboken, N.J. :
John Wiley & Sons,
©2009.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 100 | 1 | |a Turner, J. Rick. | |
| 245 | 1 | 0 | |a Integrated cardiac safety : |b assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance / |c J. Rick Turner, Todd A. Durham. |
| 260 | |a Hoboken, N.J. : |b John Wiley & Sons, |c ©2009. | ||
| 300 | |a 1 online resource (xxviii, 470 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
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| 504 | |a Includes bibliographical references (pages 397-455) and index. | ||
| 505 | 0 | |a The importance of cardiac safety assessments -- The biological basis of adverse drug reactions -- Cardiac structure and function -- Cardiac pathophysiology and disease -- Drug discovery and drug design -- Nonclinical development -- The thorough QT/QTc trial -- General safety assessments -- Therapeutic use trials and meta-analyses -- Assessment methodologies in nonexperimental postmarketing surveillance -- Postmarketing proarrhythmic cardiac safety assessments -- Generalized cardiac safety -- Medication errors, adherence, and concordance -- Future directions in drug safety. | |
| 588 | 0 | |a Print version record. | |
| 520 | |a The serious nature of cardiovascular adverse drug reactions occurring in patients makes assessment of a drug's cardiac safety profile a high priority during both development and post-approval monitoring. Integrated Cardiac Safety provides necessary guidance and methodology for professionals assessing cardiac safety of drugs throughout all stages of the drug's life, from discovery and development through postmarketing research. This self-contained, reader-friendly text is valuable to professionals in the pharmaceutical, biotechnology, and CRO industries, pharmacologists, toxicologists, governm. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Cardiovascular toxicology. | |
| 650 | 0 | |a Heart |x Effect of drugs on. | |
| 650 | 0 | |a Drugs |x Side effects |x Testing. | |
| 650 | 0 | |a Drugs |x Safety measures. | |
| 650 | 0 | |a Drugs |x Design. | |
| 650 | 0 | |a Medication errors. | |
| 650 | 2 | |a Cardiovascular Diseases |x prevention & control | |
| 650 | 2 | |a Drug Design | |
| 650 | 2 | |a Medication Errors | |
| 650 | 2 | |a Product Surveillance, Postmarketing |x methods | |
| 650 | 2 | |a Safety Management |x methods | |
| 650 | 6 | |a Toxicologie cardiovasculaire. | |
| 650 | 6 | |a Cœur |x Effets des médicaments sur. | |
| 650 | 6 | |a Médicaments |x Sécurité |x Mesures. | |
| 650 | 6 | |a Médicaments |x Conception. | |
| 650 | 6 | |a Erreurs de médication. | |
| 650 | 7 | |a HEALTH & FITNESS |x Diseases |x Heart. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Cardiology. |2 bisacsh | |
| 650 | 7 | |a Medication errors |2 fast | |
| 650 | 7 | |a Drugs |x Design |2 fast | |
| 650 | 7 | |a Cardiovascular toxicology |2 fast | |
| 650 | 7 | |a Drugs |x Safety measures |2 fast | |
| 650 | 7 | |a Heart |x Effect of drugs on |2 fast | |
| 700 | 1 | |a Durham, Todd A. | |
| 758 | |i has work: |a Integrated cardiac safety (Text) |1 https://id.oclc.org/worldcat/entity/E39PCGqddxwtBhvdRRkfw868BX |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Turner, J. Rick. |t Integrated cardiac safety. |d Hoboken, N.J. : John Wiley & Sons, ©2009 |z 0470229640 |z 9780470229644 |w (DLC) 2008022807 |w (OCoLC)229430563 |
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