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|a 10.1002/9780470423936
|b Wiley InterScience
|n http://www3.interscience.wiley.com
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245 |
0 |
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|a Gene family targeted molecular design /
|c edited by Karen E. Lackey.
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260 |
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|a Hoboken, N.J. :
|b Wiley,
|c ©2009.
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300 |
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|a 1 online resource (xvi, 347 pages, 16 unnumbered pages of plates) :
|b illustrations (some color)
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336 |
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|a text
|b txt
|2 rdacontent
|
337 |
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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347 |
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|a data file
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|a Includes bibliographical references and index.
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|a Drug discoveries by gene family / Karen E. Lackey -- G-protein coupled receptors / Stephen L. Garland and Tom D. Heightman -- Ion channels gene family : strategies for discovering ion channel drugs / Maria L. Garcia and Gregory J. Kaczorowski -- Integrins / David D. Miller -- Strategies for discovering kinase drugs / Jerry L. Adams [and others] -- Protease-directed drug discovery / Richard Sedrani, Ulrich Hommel, and Jor̈g Eder -- Small-molecule inhibitors of protein-protein interactions : challenges and prospects / Adrian Whitty -- Transporters / Anne Hersey, Frank E. Blaney, and Sandeep Modi -- Nuclear receptor drug discovery / Hiroyuki Kagechika and Aya Tanatani -- Summary and comparison of molecules designed to modulate druggable targets in the major gene families / Karen E. Lackey.
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|a Print version record.
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520 |
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|a As research progresses and information continues to proliferate in the field of molecular design for therapeutic use, there is a need for a reference that brings current theory and proven practice together in a how-to volume. This reference guides scientists new to the field on how to design small molecules that interact with critical protein targets. The chapters condense useful material into a manageable format which is carefully organized and presented. It offers an essential resource for a variety of chemists in academia, and the biotech and pharmaceutical industries, as well as profession.
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546 |
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|a English.
|
590 |
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|a ProQuest Ebook Central
|b Ebook Central Academic Complete
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650 |
|
0 |
|a Pharmacogenomics.
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650 |
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|a Drugs
|x Design.
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650 |
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|a Genes.
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1 |
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|a Drug Design
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650 |
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|a Genes
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|a Ion Channels
|x genetics
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2 |
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|a Models, Molecular
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2 |
2 |
|a Pharmacogenetics
|x methods
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650 |
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|a Pharmacogénomique.
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6 |
|a Médicaments
|x Conception.
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|a Gènes.
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650 |
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|a MEDICAL
|x Pharmacology.
|2 bisacsh
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|a Genes
|2 fast
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650 |
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7 |
|a Drugs
|x Design
|2 fast
|
650 |
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7 |
|a Pharmacogenomics
|2 fast
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700 |
1 |
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|a Lackey, Karen.
|
758 |
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|i has work:
|a Gene family targeted molecular design (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCH7cwWVRpbrCFMC9cxyB8y
|4 https://id.oclc.org/worldcat/ontology/hasWork
|
776 |
0 |
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|i Print version:
|t Gene family targeted molecular design.
|d Hoboken, N.J. : John Wiley & Sons, ©2009
|z 9780470412893
|z 0470412895
|w (DLC) 2008029607
|w (OCoLC)233678601
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|u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=406459
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