Facilitative glucose transporters in articular chondrocytes : expression, distribution and functional regulation of GLUT isoforms by hypoxia, hypoxia mimetics, growth factors and pro-inflammatory cytokines /

Articular cartilage is a unique and highly specialized avascular connective tissue in which the availability of oxygen and glucose is significantly lower than synovial fluid and plasma. Glucose is an essential source of energy during embryonic growth and fetal development and is vital for mesenchyma...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Mobasheri, A. (Ali) (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin : Springer Verlag, 2008.
Colección:Advances in anatomy, embryology, and cell biology ; 200.
Temas:
Glucose.
Articular cartilage.
Cartilage cells.
Cytokines.
Dextrose.
Glucose Transport Proteins, Facilitative > metabolism
Glucose
Cartilage, Articular
Chondrocytes
Cytokines
Arthritis > metabolism
Chondrocytes > metabolism
Cartilage articulaire.
Chondrocytes.
SCIENCE > Chemistry > Organic.
Chondrocytes > metabolism.
Glucose Transport Proteins, Facilitative > metabolism.
Arthritis > metabolism.
Biomédecine.
Sciences de la vie.
Dextrose
Articular cartilage
Cartilage cells
Internet Resources.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Introduction
  • Articular cartilage: structure, function and pathophysiology
  • Does arthritis have a nutritional aetiology?
  • Metabolic dysfunction in arthritis
  • Glucose: an essential metabolite and structural precursor for articular cartilage
  • Mammalian sugar transporter families: GLUT and SGLT
  • Molecular diversity of facilitative glucose transporters in articular chondrocytes
  • Regulation of glucose transport by non-steroidal anti-inflammatory drugs (NSAIDs)
  • Glucose transporters in the intervertebral disc
  • Glucose transporter expression and regulation in embryonic and mesenchymal stem cells
  • Concluding remarks.

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