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RNA interference /

In the last few years the major effect that RNAi has had in invertebrate systems like C.elegans and drosophila is beginning to take hold in mammalian systems through both single gene knockdown experiments and genome-scale screens. In the next decade, there will no doubt be both notable successes and...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Paddison, Patrick J., Vogt, P. K. (Peter K.), 1932-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Berlin : Springer, ©2008.
Colección:Current topics in microbiology and immunology ; 320.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • RNA interference in mammalian cell systems / Patrick J. Paddison
  • RNAi pathway in C. elegans: the argonautes and collaborators / Marie-Eve L. Boisvert and Martin J. Simard
  • Genetics and biochemistry of RNAi in drosophila / Harsh H. Kavi [and others]
  • Role of dicer in posttranscriptional RNA silencing / Lukasz Jaskiewicz and Witold Filipowicz
  • The mechanism of RNase III action: how dicer dices / Xinhua Ji
  • MicroRNA metabolism in plants / Xuemei Chen
  • Structure-function relationships among RNA-dependent RNA polymerases / Kenneth K.-S. Ng, Jamie J. Arnold, and Craig E. Cameron
  • RNAi-mediated chromatin silencing in fission yeast / Sharon A. White and Robin C. Allshire
  • A role for RNAi in heterochromatin formation in drosophila / Nicole C. Riddle and Sarah C.R. Elgin
  • RNA mediated transcriptional gene silencing in human cells / Kevin V. Morris
  • RNA silencing in mammalian oocytes and early embryos / Petr Svoboda
  • Identifying human microRNAs / Isaac Bentwich.