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Thiol metabolism and redox regulation of cellular functions /

This volume contains contributions by some of the leading scientists in the field of thiol oxidation/reduction (redox) biochemistry. It is focused on the biological/pathophysiological implications of newly-discovered functions of cellular thiols, such as glutathione in the first place.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: NATO Advanced Research Workshop on Thiol Metabolism and Redox Regulation of Cellular Functions
Otros Autores: Pompella, Alfonso, Bánhegyi, Gábor, Wellman-Rousseau, Maria
Formato: Electrónico Congresos, conferencias eBook
Idioma:Inglés
Publicado: Amsterdam ; Washington, DC : IOS Press, ©2002.
Colección:NATO science series. Life and behavioural sciences ; v. 347.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Oxidative signaling and glutathione synthesis
  • Cell survival and changes in gene expression in cells unable to synthesize glutathione
  • Role of glutathione in the regulation of liver metabolism
  • Glutathione transport in the endo/sarcoplasmic reticulum
  • Role of ascorbate in oxidative protein folding
  • Cytophotometric investigations on oscillating thiol-disulfide equilibria and oxidized protein sulfur
  • Protection by pantothenic acid against apoptosis and cell damage by oxygen free radicals
  • the role of glutathione
  • Thiols as major determinants of the total antioxidant capacity
  • Enzymes of the thio9l-dependent hydroperoxide metabolism in pathogens as potential drug targets
  • Is there a role of glutathione peroxidases in signaling and differentiation?
  • Multidrug resistance-associated proteins: export pumps for conjugates with glutathione, glucuronate or sulfate
  • Detoxification of eletrophilic compounds by glutathione s-transferase catalysis: determinants of individual response to chemical carcinogens and chemotherapeutic drugs?
  • Transcriptional regulation of glutathione s-transferase P1-1 in human leukemia
  • Mechanism of [gamma]-glutamyltranspeptidase folding and activation in the endoplasmic reticulum.
  • The role of [gamma]-glutamyl transpeptidase in the biosynthesis of glutathione
  • Role of [gamma]-glutamyltransferase in the homeostasis of glutathione during oxidative and nitrosative stress
  • The importance of gamma-glutamyl transferase in lung glutathione homeostasis and antioxidant defense
  • The role of gamma-glutamyltranspeptidase in the metabolism and cytotoxicity of 4-hydroxynonenal-glutathione conjugate: evidence and hypothesis
  • [gamma]-glutamyltransferase-dependent prooxidant reactions: a factor in multiple processes
  • Serum gamma-glutamyl transpeptidase: a prognostic marker in cardiovascular diseases
  • Lipoic acid: a multifunctional antioxidant
  • Is glutathione an important neuroprotective effector molecule against amyloid beta toxicity?
  • Antioxidants in cancer therapy: is there a rationale to recommend antioxidants during cancer therapy?
  • Disulfide exchange in CD4
  • Redox regulation in protein folding and chaperone function
  • Reduction of the endoplasmic reticulum accompanies the oxidative damage of diabetes mellitus
  • Analytical developments in the assay of intra- and extracellular GSH homeostasis
  • Signalling potential and protein modifying ability of physiological thiols
  • Redox signaling and the map kinase pathways
  • Redox regulation of mitochondrial permeability transition: contrasting effects of lipoic acid and its positively charged analog LA-plus
  • Redox state of glutathione and.