The art of drug synthesis /

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The Art of Drug Synthesis illustrates how chemistry, biology, pharmacokinetics, and a host of other disciplines come together to produce successful medicines. The authors have compiled a collection of 21 representative categories of drugs, from which they have selected as examples many of the best-s...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Johnson, Douglas S. (Douglas Scott), 1968-, Li, Jie Jack
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Hoboken, N.J. : Wiley-Interscience, [2007]
Temas:
Drugs > Design.
Pharmaceutical chemistry.
Drug Design
Chemistry, Pharmaceutical > methods
Chemistry, Pharmaceutical
Médicaments > Conception.
Chimie pharmaceutique.
MEDICAL > Drug Guides.
MEDICAL > Pharmacology.
MEDICAL > Pharmacy.
MEDICAL > Nursing > Pharmacology.
Drugs > Design
Pharmaceutical chemistry
Acceso en línea:Texto completo
Tabla de Contenidos:
  • The role of medicinal chemistry in drug discovery / John A. Lowe III
  • Process research: how much? how soon? / Neal G. Anderson
  • Aromatase inhibitors for breast cancer : exemestane (Aromasin), anastrozole (Arimidex), and letrozole (Femara) / Jie Jack Li
  • Quinolone antibiotics : levofloxacin (Levaquin), moxifloxacin (Avelox), gemifloxacin (Factive), and garenoxacin (T-3811) / Chris Limberakis
  • Triazole antifungals : itraconazole (Sporanox), fluconazole (Diflucan), voriconazole (Vfend), and fosfluconazole (Prodif) / Andrew S. Bell
  • Non-nucleoside HIV reverse transcriptase inhibitors / Arthur Harms
  • Neuraminidase inhibitors for influenza : oseltamivir phosphate (Tamiflu) and zanamivir (Relenza) / Douglas S. Johnson and Jie Jack Li
  • Peroxisome proliferator-activated receptor (PPAR) agonists for type 2 diabetes / Jin Li
  • Angiotensin AT1 antagonists for hypertension / Larry Yet
  • Leading ACE inhibitors for hypertension / Victor J. Cee and Edward J. Olhava
  • Dihydropyridine calcium channel blockers for hypertension / Daniel P. Christen
  • Second-generation HMG-CoA reductase inhibitors / Jeffrey A. Pfefferkorn
  • Cholesterol absorption inhibitors: ezetimibe (zetia) / Stuart B. Rosenblum
  • Dual selective serotonin and norepinephrine reuptake inhibitors (SSNRIs) for depression / Marta Piñeiro-Núñez
  • GABA receptor agonists for insomnia : zolpidem (Ambien), zaleplon (Sonata), eszopiclone (Estorra, Lunesta), and indiplon / Peter R. Guzzo
  • Ligands: neurontin (Gabapentin) and lyrica (Pregabalin) / Po-Wai Yuen
  • Approved treatments for attention deficit hyperactivity disorder : amphetamine (Adderall), methylphenidate (Ritalin), and atomoxetine (Straterra) / David L. Gray.

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