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|a Vijg, Jan.
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|a Aging of the genome :
|b the dual role of DNA in life and death /
|c Jan Vijg.
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|a Oxford ;
|a New York :
|b Oxford University Press,
|c 2007.
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300 |
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|a 1 online resource (x, 372 pages) :
|b illustrations
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336 |
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|a text
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|2 rdacontent
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|a Print version record.
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|a Includes bibliographical references (pages 309-351) and index.
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|a The logic of aging -- Genome structure and function -- Genome maintenance -- Genome instability and accerated aging -- The aging genome -- From genome to phenome -- A genomic limit to life?
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|a Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology. - ;Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technol.
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590 |
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|a ProQuest Ebook Central
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|a eBooks on EBSCOhost
|b EBSCO eBook Subscription Academic Collection - Worldwide
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650 |
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|a Aging
|x Genetic aspects.
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650 |
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|a Apoptosis.
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|a Genomes.
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|a Developmental genetics.
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|a DNA damage.
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1 |
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|a Aging
|x genetics
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|a Apoptosis
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|a DNA Damage
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|a DNA
|x genetics
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|a Genome
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|a Vieillissement
|x Aspect génétique.
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|a Apoptose.
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|a Génomes.
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|a Génétique du développement.
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|a ADN
|x Lésions.
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|a MEDICAL
|x Neuroscience.
|2 bisacsh
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|a PSYCHOLOGY
|x Neuropsychology.
|2 bisacsh
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|a Aging
|x Genetic aspects
|2 fast
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|a Apoptosis
|2 fast
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7 |
|a Developmental genetics
|2 fast
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650 |
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|a DNA damage
|2 fast
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7 |
|a Genomes
|2 fast
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758 |
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|i has work:
|a Aging of the genome (Text)
|1 https://id.oclc.org/worldcat/entity/E39PCGWbGM4rvggvm3xGRBhjFq
|4 https://id.oclc.org/worldcat/ontology/hasWork
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776 |
0 |
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|i Print version:
|a Vijg, Jan.
|t Aging of the genome.
|d Oxford ; New York : Oxford University Press, 2007
|z 9780198569237
|z 0198569238
|w (DLC) 2006039672
|w (OCoLC)76864399
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