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Three-dimensional electron microscopy of macromolecular assemblies : visualization of biological molecules in their native state /
Cryoelectron microscopy of biological molecules is among the hottest growth areas in biophysics & structural biology at present.
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Oxford ; New York :
Oxford University Press,
2006.
|
| Edición: | 2nd ed. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 049 | |a UAMI | ||
| 100 | 1 | |a Frank, J. |q (Joachim), |d 1940- |1 https://id.oclc.org/worldcat/entity/E39PBJm4WHmQCTmmPDP9dPQwmd | |
| 245 | 1 | 0 | |a Three-dimensional electron microscopy of macromolecular assemblies : |b visualization of biological molecules in their native state / |c Joachim Frank. |
| 250 | |a 2nd ed. | ||
| 260 | |a Oxford ; |a New York : |b Oxford University Press, |c 2006. | ||
| 300 | |a 1 online resource (xiv, 410 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a data file |2 rda | ||
| 504 | |a Includes bibliographical references (pages 345-398) and index. | ||
| 520 | 8 | |a Cryoelectron microscopy of biological molecules is among the hottest growth areas in biophysics & structural biology at present. | |
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a CHAPTER 1 Introduction; 1 The Electron Microscope and Biology; 1.1 General Remarks; 1.2 Three-Dimensional Electron Microscopy; 2 Single-Particle Versus Crystallographic Analysis; 3 Crystallography without Crystals; 4 Toward a Unified Approach to Structural Analysis of Macromolecules; 5 Single-Particle Reconstruction, Macromolecular Machines, and Structural Proteomics; 6 The Electron Microscope and the Computer; CHAPTER 2 Electron Microscopy of Macromolecular Assemblies; 1 Principle of the Transmission Electron Microscope; 2 Specimen Preparation Methods; 2.1 Introduction. | |
| 505 | 8 | |a 2.2 Negative Staining2.3 Glucose Embedment; 2.4 Use of Tannic Acid; 2.5 Ice-Embedded Specimens; 2.6 Hybrid Techniques: Cryo-Negative Staining; 2.7 Labeling with Gold Clusters; 2.8 Support Grids; 3 Principle of Image Formation in the Transmission Electron Microscope; 3.1 Introduction; 3.2 The Weak-Phase Object Approximation; 3.3 The Contrast Transfer Theory; 3.4 Amplitude Contrast; 3.5 Formulation of Bright-Field Image Formation Using Complex Atomic Scattering Amplitudes; 3.6 Optical and Computational Diffraction Analysis-The Power Spectrum; 3.7 Determination of the Contrast Transfer Function. | |
| 505 | 8 | |a 3.8 Instrumental Correction of the Contrast Transfer Function3.9 Computational Correction of the Contrast Transfer Function; 3.10 Locally Varying CTF and Image Quality; 4 Special Imaging Techniques and Devices; 4.1 Low-Dose Electron Microscopy; 4.2 Spot Scanning; 4.3 Energy Filtration; 4.4 Direct Image Readout and Automated Data Collection; CHAPTER 3 Two-Dimensional Averaging Techniques; 1 Introduction; 1.1 The Different Sources and Types of Noise; 1.2 Principle of Averaging: Historical Notes; 1.3 Equivalence between Averaging and Quasi-Optical Fourier Filtration. | |
| 505 | 8 | |a 1.4 A Discourse on Terminology: Views Versus Projections1.5 The Role of Two-Dimensional Averaging in the Three-Dimensional Analysis of Single Molecules; 1.6 Origins of Orientational Preferences; 2 Digitization and Selection of Particles; 2.1 Hardware for Digitization; 2.2 The Sampling Theorem; 2.3 Interactive Particle Selection; 2.4 Automated Particle Selection; 3 Alignment Methods; 3.1 Quantitative Definitions of Alignment; 3.2 Homogeneous Versus Heterogeneous Image Sets; 3.3 Translational and Rotational Cross-Correlation; 3.4 Reference-Based Alignment Techniques. | |
| 505 | 8 | |a 3.5 Reference-Free Alignment Techniques3.6 Alignment Using the Radon Transform; 4 Averaging and Global Variance Analysis; 4.1 The Statistics of Averaging; 4.2 The Variance Map and the Analysis of Statistical Significance; 4.3 Signal-to-Noise Ratio; 5 Resolution; 5.1 The Concept of Resolution; 5.2 Resolution Criteria; 5.3 Resolution and Cross-Resolution; 5.4 Resolution-Limiting Factors; 5.5 Statistical Requirements following the Physics of Scattering; 5.6 Noise Filtering; 6 Validation of the Average Image; CHAPTER 4 Multivariate Data Analysis and Classification of Images; 1 Introduction. | |
| 546 | |a English. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Three-dimensional imaging in biology. | |
| 650 | 0 | |a Electron microscopy. | |
| 650 | 2 | |a Microscopy, Electron | |
| 650 | 2 | |a Microscopy, Electron |x methods | |
| 650 | 2 | |a Imaging, Three-Dimensional | |
| 650 | 2 | |a Imaging, Three-Dimensional |x methods | |
| 650 | 2 | |a Macromolecular Substances |x analysis | |
| 650 | 2 | |a Image Processing, Computer-Assisted | |
| 650 | 6 | |a Imagerie tridimensionnelle en biologie. | |
| 650 | 6 | |a Microscopie électronique. | |
| 650 | 7 | |a electron microscopy. |2 aat | |
| 650 | 7 | |a NATURE |x Reference. |2 bisacsh | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x General. |2 bisacsh | |
| 650 | 7 | |a SCIENCE |x Life Sciences |x Biology. |2 bisacsh | |
| 650 | 7 | |a Electron microscopy |2 fast | |
| 650 | 7 | |a Three-dimensional imaging in biology |2 fast | |
| 650 | 1 | 7 | |a Elektronenmicroscopie. |2 gtt |
| 650 | 1 | 7 | |a Driedimensionale afbeeldingen. |2 gtt |
| 650 | 1 | 7 | |a Macromoleculen. |2 gtt |
| 758 | |i has work: |a Three-dimensional electron microscopy of macromolecular assemblies (Text) |1 https://id.oclc.org/worldcat/entity/E39PCGMGwjPdhK88wMG7pkRvVC |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Frank, J. (Joachim), 1940- |t Three-dimensional electron microscopy of macromolecular assemblies. |b 2nd ed. |d Oxford ; New York : Oxford University Press, 2006 |z 0195150961 |z 0195182189 |w (DLC) 2004018762 |w (OCoLC)56368337 |
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