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Drug membrane interactions : analysis, drug distribution, modeling /
Barrier, reservoir, target site - those are but some of the possible functions of biological lipid membranes in the complex interplay of drugs with the organism. A detailed knowledge of lipid membranes and of the various modes of drug-membrane interaction is therefore the prerequisite for a better u...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Weinheim :
Wiley-VCH,
2002.
|
| Colección: | Methods and principles in medical chemistry ;
15. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 060 | 4 | |a ELECTRONIC BOOK | |
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| 049 | |a UAMI | ||
| 100 | 1 | |a Seydel, J. K. |q (Joachim Karl) | |
| 245 | 1 | 0 | |a Drug membrane interactions : |b analysis, drug distribution, modeling / |c Joachim K. Seydel, Michael Wiese ; eds.: Raimund Mannhold [and others]. |
| 260 | |a Weinheim : |b Wiley-VCH, |c 2002. | ||
| 300 | |a 1 online resource (approximately 354 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Methods and principles in medical chemistry ; |v 15 | |
| 588 | 0 | |a Print version record. | |
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Drug-Membrane Interactions; Contents; Preface; Foreword; Introduction; 1 Function, Composition, and Organization of Membranes; 2 Octanol-Water Partitioning versus Partitioning into Membranes; 3 Analytical Tools for the Analysis and Quantification of Drug-Membrane Interactions; 4 Drug-Membrane Interaction and Pharmacokinetics of Drugs; 5 Drug-Membrane Interactions and Pharmacodynamics; 6 Computer Simulation of Phospholipids and Drug-Phospholipid Interactions; Index. | |
| 520 | |a Barrier, reservoir, target site - those are but some of the possible functions of biological lipid membranes in the complex interplay of drugs with the organism. A detailed knowledge of lipid membranes and of the various modes of drug-membrane interaction is therefore the prerequisite for a better understanding of drug action. Many of today's pharmaceuticals are amphiphilic or catamphiphilic, enabling them to interact with biological membranes. Crucial membrane properties are surveyed and techniques to elucidate drug-membrane interactions presented, including computer-aided predictions. Effect. | ||
| 546 | |a English. | ||
| 590 | |a ProQuest Ebook Central |b Ebook Central Academic Complete | ||
| 650 | 0 | |a Drugs |x Structure-activity relationships. | |
| 650 | 0 | |a Drugs |x Mechanism of action. | |
| 650 | 0 | |a Bilayer lipid membranes |x Effect of drugs on. | |
| 650 | 0 | |a Pharmacokinetics. | |
| 650 | 0 | |a Mechanism of action (Biochemistry) | |
| 650 | 2 | |a Pharmacokinetics | |
| 650 | 2 | |a Membrane Lipids |x pharmacology | |
| 650 | 6 | |a Médicaments |x Relations structure-activité. | |
| 650 | 6 | |a Mécanisme d'action (Biochimie) | |
| 650 | 6 | |a Membranes lipidiques bimoléculaires |x Effets des médicaments sur. | |
| 650 | 6 | |a Pharmacocinétique. | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a Pharmacokinetics |2 fast | |
| 650 | 7 | |a Drugs |x Mechanism of action |2 fast | |
| 650 | 7 | |a Drugs |x Structure-activity relationships |2 fast | |
| 758 | |i has work: |a Drug-membrane interactions (Text) |1 https://id.oclc.org/worldcat/entity/E39PCGycmPcyGY8Xq6FbhgFpCP |4 https://id.oclc.org/worldcat/ontology/hasWork | ||
| 776 | 0 | 8 | |i Print version: |a Seydel, J.K. (Joachim Karl). |t Drug-membrane interactions. |d Weinheim : Wiley-InterScience, ©2002 |z 3527304274 |w (OCoLC)49635333 |
| 830 | 0 | |a Methods and principles in medical chemistry ; |v 15. | |
| 856 | 4 | 0 | |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=481433 |z Texto completo |
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