Tabla de Contenidos:
  • COLLOQUIUM ON COMPUTATIONAL BIOMOLECULAR SCIENCE
  • NATIONAL ACADEMY OF SCIENCES
  • COMPLETED NAS COLLOQUIA
  • COMPLETED NAS COLLOQUIA
  • PROGRAM
  • LIST OF ATTENDEES
  • Contents
  • Computational biomolecular science
  • Measuring genome evolution
  • Methodological Issues in Comparisons of Genomes
  • Comparing Genomes as “Bags of Genesâ€?
  • Measuring Correlations Between Genes
  • Comparing Rates of Genome Evolution
  • SMART, a simple modular architecture research tool: Identification of signaling domains
  • METHODS
  • RESULTS
  • DISCUSSION
  • Highly specific protein sequence motifs for genome analysisMETHODS
  • RESULTS
  • DISCUSSION
  • A statistical mechanical model for B-hairpin kinetics
  • Coupling the folding of homologous proteins
  • DISCUSSION
  • Photoactive yellow protein: A structural prototype for the three-dimensional fold of the PAS domain superfamily
  • METHODS
  • RESULTS
  • DISCUSSION
  • New methods of structure refinement for macromolecular structure determination by NMR
  • Estimation of evolutionary distances under stationary and nonstationary models of nucleotide substitution
  • Stationary ModelsA General Measure of Rate Variation Among Sites
  • Nonstationary Models
  • Discussion
  • Precise sequence complementarity between yeast chromosome ends and two classes of just-subtelomeric sequences
  • RESULTS
  • DISCUSSION
  • A unified statistical framework for sequence comparison and structure comparison
  • DISCUSSION AND CONCLUSION
  • Folding funnels and frustration in off-lattice minimalist protein landscapes
  • A Summary of Lattice Minimalist Models
  • The B-Barrel Model
  • Signatures of Good and Bad Folders
  • Concluding Remarks
  • Optimizing the stability of single-chain proteins by linker length and composition mutagenesisMATERIALS AND METHODS
  • RESULTS
  • DISCUSSION
  • Architecture and mechanism of the light-harvesting apparatus of purple bacteria
  • Structure of Light-Harvesting Complexes
  • Mechanisms of Excitation Transfer
  • Other Photosynthetic Organisms
  • Electrostatic steering and ionic tethering in enzyme- ligand binding: Insights from simulations
  • ELECTROSTATIC STEERING
  • IONIC TETHERING