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043 |a n-us---  |a d------ 
050 4 |a RA638  |b .N49eb Vol. 2 
060 4 |a QW 805  |b I59n 1985 
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072 7 |a MED  |x 028000  |2 bisacsh 
082 0 4 |a 614.4/7/0973  |2 22 
049 |a UAMI 
245 0 0 |a New vaccine development :  |b establishing priorities.  |n Volume II,  |p Diseases of importance in Developing Countries /  |c part two of a two-part Study by the Committee on Issues and Priorities for New Vaccine Development, Division of Health Promotion and Disease Prevention, and Division of International Health, Institute of Medicine. 
246 3 0 |a Diseases of importance in Developing Countries 
260 |a Washington, D.C. :  |b National Academy Press,  |c 1986. 
300 |a 1 online resource (1 volume) 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
500 |a Prepared for the National Institute of Allergy and Infectious Diseases. 
504 |a Includes bibliographical references and indexes. 
588 0 |a Print version record. 
505 0 |a New Vaccine Development Establishing Priorities -- Copyright -- Acknowledgements -- Preface -- Abstract -- Contents -- Summary -- SELECTION OF CANDIDATES -- DETERMINATION OF HEALTH BENEFITS -- Disease Burden Estimates -- Infant Mortality Equivalence Values -- Total Disease Burden Values -- VACCINE CHARACTERISTICS -- Predictions of Vaccine Development -- Definition of Probable Vaccine Target Population -- Treatment of Vaccine Utilization -- Estimation of Time to Licensure, Time to Vaccine Adoption, and Delay of Vaccination Benefits: Discou ... 
505 8 |a Estimation of Vaccine Preventable IllnessCalculation of Potential Health Benefits for Each Vaccine -- Cost Calculations -- INTERPRETATION OF RESULTS -- FINDINGS, CONCLUSIONS, RECOMMENDATIONS -- REFERENCE -- 2 Priority Setting for Health-Related Investments: A Review of Methods -- METHODS FOR PROJECT RANKING AND SELECTION -- MULTIATTRIBUTE ACCOUNTING -- MULTIATTRIBUTE SCORING -- DECISION ANALYSIS WITH MULTIPLE OBJECTIVES -- COST-EFFECTIVENESS AND COST-UTILITY ANALYSIS -- BENEFIT-COST ANALYSIS -- SELECTION OF AN APPROACH 
505 8 |a ISSUES IN PROJECT RANKING METHODOLOGIESSources of Estimates -- Sequential or “Lexicographicâ€? Methods -- Interdependence Among Projects -- The “Portfolioâ€? Question -- SUMMARY -- REFERENCES -- 3 Overview of the Analytic Approach -- METHOD -- Calculation Procedures -- INTERPRETATION OF RESULTS -- GUIDELINES -- Step 1 -- Step 2 -- SUMMARY -- REFERENCE -- 4 Comparison of Disease Burdens -- ELEMENTS OF THE SYSTEM FOR COMPARING MORBIDITY AND MORTALITY BURDENS ARISING FROM VARIOUS DISEASES -- Trade-Off Values 
505 8 |a Expression of Morbidity and Mortality BurdensProcedures Used in Deriving Disease Estimates -- Limitations of the Current Estimates -- VALUE JUDGMENTS IN QUANTIFYING MORBIDITY AND MORTALITY -- IME Perspective Used in This Study -- The Effect of Adopting Other IME Perspectives -- COMPARISON OF COSTS ASSOCIATED WITH DISEASES -- Estimating Aggregate Direct Costs of Diseases in the Developing World -- Estimating Costs for Diseases in Specific Countries or Regions -- Indirect Costs -- FINDINGS -- LIMITATIONS OF THE PROPOSED SYSTEM -- SUMMARY AND CONCLUSIONS 
505 8 |a RECOMMENDATIONSREFERENCES -- 5 Predictions on Vaccine Development -- THE NEED FOR PREDICTIONS -- SELECTION OF CANDIDATES -- VACCINE CANDIDATES AND TARGET POPULATIONS -- PREDICTIONS ON VACCINE DEVELOPMENT -- Probability of Successful Development -- Cost of Development -- Time to Licensure -- PREDICTIONS ON VACCINE CHARACTERISTICS -- Efficacy -- Adverse Reactions -- Production Technology, Delivery Requirements, and Cost per Dose -- Number of Doses and Route of Administration -- CONCLUSIONS -- REFERENCE 
590 |a eBooks on EBSCOhost  |b EBSCO eBook Subscription Academic Collection - Worldwide 
590 |a ProQuest Ebook Central  |b Ebook Central Academic Complete 
650 0 |a Vaccines  |x Research  |x Government policy. 
650 0 |a Vaccination  |z United States. 
650 0 |a Vaccination  |z Developing countries. 
650 0 |a Health planning. 
650 0 |a Medical policy. 
650 1 2 |a Health Planning 
650 1 2 |a Communicable Disease Control 
650 1 2 |a Vaccines  |x supply & distribution 
650 2 |a Developing Countries 
650 1 2 |a Health Policy 
650 6 |a Vaccins  |x Recherche  |x Politique gouvernementale. 
650 6 |a Vaccination  |z États-Unis. 
650 6 |a Santé publique  |x Planification. 
650 6 |a Politique sanitaire. 
650 7 |a MEDICAL  |x Health Risk Assessment.  |2 bisacsh 
650 7 |a MEDICAL  |x Epidemiology.  |2 bisacsh 
650 7 |a Medical policy  |2 fast 
650 7 |a Health planning  |2 fast 
650 7 |a Vaccination  |2 fast 
651 7 |a United States  |2 fast  |1 https://id.oclc.org/worldcat/entity/E39PBJtxgQXMWqmjMjjwXRHgrq 
651 7 |a Developing countries  |2 fast 
710 2 |a Institute of Medicine (U.S.).  |b Committee on Issues and Priorities for New Vaccine Development. 
710 2 |a National Institute of Allergy and Infectious Diseases (U.S.) 
758 |i has work:  |a Vol. 1 Diseases of importance in the United States New vaccine development: establishing priorities (Text)  |1 https://id.oclc.org/worldcat/entity/E39PCGYDdWc3wHqHYxtRym8JrC  |4 https://id.oclc.org/worldcat/ontology/hasWork 
776 0 8 |i Print version:  |t New vaccine development.  |d Washington, D.C. : National Academy Press, 1986  |z 0309036798  |w (DLC) 84062037  |w (OCoLC)11667096 
856 4 0 |u https://ebookcentral.uam.elogim.com/lib/uam-ebooks/detail.action?docID=3377441  |z Texto completo 
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