Acute exposure guideline levels for selected airborne chemicals. Volume 1 /

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: National Research Council (U.S.). Subcommittee on Acute Exposure Guideline Levels
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Washington, D.C. : National Academy Press, ©2000.
Colección:Compass series (Washington, D.C.)
Temas:
Gases, Asphyxiating and poisonous.
Hazardous substances > Environmental aspects.
Hazardous substances > Health aspects.
Chemicals > Physiological effect.
Chemicals > Health aspects.
Environmental Exposure > standards
Hazardous Substances > standards
Air Pollutants > standards
Hazardous Substances > toxicity
Gaz asphyxiants et délétères.
Substances dangereuses > Aspect sanitaire.
Produits chimiques > Effets physiologiques.
MEDICAL > Toxicology.
Chemicals > Health aspects
Chemicals > Physiological effect
Gases, Asphyxiating and poisonous
Hazardous substances > Environmental aspects
Hazardous substances > Health aspects
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Acute Exposure Guideline Levels for Selected Airborne Chemicals
  • Copyright
  • Preface
  • Contents
  • Acute Exposure Guideline Levels for Selected Airborne Chemicals
  • Introduction
  • SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING AEGLS
  • REVIEW OF AEGL REPORTS
  • REFERENCES
  • Roster of the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances
  • COMMITTEE MEMBERS
  • OAK RIDGE NATIONAL LABORATORY STAFF
  • NATIONAL ADVISORY COMMITTEE STAFF
  • Appendix
  • 1 Aniline1 Acute Exposure Guideline Levels
  • SUMMARY
  • 1. INTRODUCTION2. HUMAN TOXICITY DATA
  • 2.1. Acute Lethality
  • 2.2. Nonlethal Toxicity
  • 2.2.1. Experimental Studies
  • 2.2.2. Epidemiology Studies
  • 2.2.3. Accidents
  • 2.3. Developmental and Reproductive Effects
  • 2.4. Genotoxicity
  • 2.5. Carcinogenicity
  • 2.6. Summary
  • 3. ANIMAL TOXICITY DATA
  • 3.1. Acute Lethality
  • 3.1.1. Rats
  • 3.1.2. Mice
  • 3.2. Nonlethal Toxicity
  • 3.2.1. Dogs
  • 3.2.2. Rats
  • 3.2.3. Mice
  • 3.2.4 Guinea pigs
  • 3.3. Developmental and Reproductive Effects
  • 3.4. Genotoxicity
  • 3.5. Carcinogenicity
  • 3.6. Summary4. SPECIAL CONSIDERATIONS
  • 4.1. Metabolism and Disposition
  • 4.2. Mechanism of Toxicity
  • 4.3. Structure-Activity Relationships
  • 4.4. Other Relevant Information
  • 4.4.1. Susceptible Subpopulations
  • 4.4.2. Species Differences
  • 4.4.3. Concentration-Exposure Duration Relationship
  • 5. DATA ANALYSIS FOR AEGL-1
  • 5.1. Human Data Relevant to AEGL-1
  • 5.2. Animal Data Relevant to AEGL-1
  • 5.3. Derivation of AEGL-1
  • 6. DATA ANALYSIS FOR AEGL-2
  • 6.1. Human Data Relevant to AEGL-2
  • 6.2. Animal Data Relevant to AEGL-2
  • 6.3. Derivation of AEGL-27. DATA ANALYSIS FOR AEGL-3
  • 7.1. Human Data Relevant to AEGL-3
  • 7.2. Animal Data Relevant to AEGL-3
  • 7.3. Derivation of AEGL-3
  • 8. SUMMARY OF AEGLS
  • 8.1. AEGL Values and Toxicity Endpoints
  • 8.2. Comparisons with Other Standards and Guidelines
  • 8.3. Data Adequacy and Research Needs
  • 9. REFERENCES
  • 2 Arsine1 Acute Exposure Guideline Levels
  • SUMMARY
  • 1. INTRODUCTION
  • 2. HUMAN TOXICITY DATA
  • 2.1. Acute Lethality
  • 2.1.1. Case Reports
  • 2.2. Nonlethal Toxicity
  • 2.2.1. Case Reports
  • 2.2.2. Epidemiologic Studies2.3. Developmental and Reproductive Toxicity
  • 2.4. Genotoxicity
  • 2.5. Carcinogenicity
  • 2.6. Summary
  • 3. ANIMAL TOXICITY DATA
  • 3.1. Acute Lethality
  • 3.1.1. Nonhuman Primates
  • 3.1.2. Dogs
  • 3.1.3. Cats
  • 3.1.4 Rats
  • 3.1.5. Mice
  • 3.2. Nonlethal Toxicity
  • 3.2.1. Nonhuman Primates
  • 3.2.2. Rats
  • 3.2.3. Mice
  • 3.2.4. Hamsters
  • 3.3. Developmental/Reproductive Toxicity
  • 3.3.1. Rats
  • 3.3.2. Mice
  • 3.4. Genotoxicity
  • 3.5. Carcinogenicity
  • 3.6. Summary
  • 4. SPECIAL CONSIDERATIONS

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