Tabla de Contenidos:
  • IMMUNIZATION SAFETY REVIEW
  • Copyright
  • Acknowledgments
  • Contents
  • Executive Summary
  • PLAUSIBILITY ASSESSMENT
  • Biological Plausibility
  • Causality
  • SIGNIFICANCE ASSESSMENT
  • PUBLIC HEALTH RESPONSE
  • Policy Review and Analysis
  • Public Health and Biomedical Research
  • Epidemiological Research
  • Clinical Research
  • Basic Science Research
  • Communications
  • SUMMARY
  • REFERENCES
  • Immunization Safety Review: Thimerosal-Containing Vaccines and Neurodevelopmental Disorders
  • ORIGINS OF THE IMMUNIZATION SAFETY REVIEW PROJECT
  • THE CHARGE TO THE COMMITTEETHE STUDY PROCESS
  • THE FRAMEWORK FOR ASSESSING CAUSALITY
  • UNDER REVIEW: THIMEROSAL-CONTAINING VACCINES AND NEURODEVELOPMENTAL DISORDERS
  • Thimerosal in Vaccines
  • Neurodevelopmental Disorders
  • Autism
  • Attention Deficit/Hyperactivity Disorder (ADHD)
  • Speech or Language Delay
  • PLAUSIBILITY ASSESSMENT
  • Evidence Regarding Association: Biological Plausibility
  • Mercury Toxicokinetics
  • Comparisons of Ethylmercury and Methylmercury
  • Health Effects of High-Dose Exposures to Thimerosal, Ethylmercury, and Methylmercury
  • Health Effects of Low-Dose Exposures to Thimerosal and MethylmercuryInvestigations Related to Mercury and Heavy Metals in Children with Autism
  • Application of Methylmercury Exposure Guidelines to Thimerosal Exposure from Vaccines
  • Biological Plausibility Argument
  • Evidence Regarding Association: Case Reports, Case Series, and Uncontrolled and Controlled Epidemiological Studies
  • Case Reports and Case Series
  • Epidemiological Studies
  • CAUSALITY ARGUMENT
  • SIGNIFICANCE ASSESSMENT
  • Concern Regarding Neurodevelopmental Disorders
  • Continued Exposure to ThimerosalUse of Thimerosal-Containing Vaccines in Other Countries
  • Confusion from Changes in Hepatitis B Immunization Policy
  • Trust in the Safety of Vaccines
  • Conclusion
  • RECOMMENDATIONS REGARDING THE PUBLIC HEALTH RESPONSE
  • Policy Review and Analysis
  • Public Health and Biomedical Research
  • Epidemiological Studies
  • Clinical Studies
  • Basic Science Studies
  • Communications
  • SUMMARY
  • REFERENCES
  • Appendix A Immunization Safety Review: Measles-Mumps-Rubella Vaccine and Autism Executive Summary
  • OVERVIEW OF THE IMMUNIZATION SAFETY REVIEW PROJECTTHE HYPOTHESIZED RELATIONSHIP BETWEEN MMR AND AUTISM
  • PLAUSIBILITY ASSESSMENT
  • SIGNIFICANCE ASSESSMENT
  • RECOMMENDATIONS
  • Public Health Response
  • Policy Review
  • Research Regarding MMR and ASD
  • Communications
  • General and Crosscutting Issues
  • SUMMARY
  • REFERENCES
  • Appendix B Monday, July 16, 2001 Meeting Agenda
  • Appendix C Thimerosal Content in Licensed Vaccines
  • Appendix D Immunization Safety Review Committee Biosketches
  • Board on Health Promotion Disease Prevention Liaison