I Domain Integrins

The integrin family is composed of 24 members and approximately ten years ago (2003) we published a book devoted to the nine I domain integrin subunits. In this second edition, I am pleased that most of the original authors have been able to contribute to the updated version. I domain containing int...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Gullberg, Donald (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2014.
Edición:1st ed. 2014.
Colección:Advances in Experimental Medicine and Biology, 819
Temas:
Medicine-Research.
Biology-Research.
Life sciences.
Medical genetics.
Clinical biochemistry.
Biomedical Research.
Life Sciences.
Medical Genetics.
Medical Biochemistry.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Preface
  • 1 Evolution of integrin I domains
  • 2 Integrin a1b1
  • 3 Integrin a2b1
  • 4 Integrin a10b1- a collagen receptor critical in skeletal development
  • 5 Integrin a11b1 - a major collagen receptor on fibroblastic cells
  • 6 Regulation of integrin activity by phosphorylation
  • 7 Integrin aEb7:molecular features and functional significance in the immune system
  • 8 Structural aspects of integrins
  • 9 Integrin recognition motifs in the human collagens
  • 10 Cellular signalling by collagen-binding integrins
  • 11 The therapeutic potential of I-domain integrins
  • Index.

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