The Biochemistry of Retinoic Acid Receptors I: Structure, Activation, and Function at the Molecular Level

A role for vitamin A in living organisms has been known throughout human history. In the last 100 years, the biochemical nature of vitamin A and its active derivative, retinoic acid, its physiological impact on growth processes and the essential details of its mechanism of action have been revealed...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Asson-Batres, Mary Ann (Editor ), Rochette-Egly, Cécile (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2014.
Edición:1st ed. 2014.
Colección:Subcellular Biochemistry, 70
Temas:
Medicine > Research.
Biology > Research.
Molecular genetics.
Social sciences.
Humanities.
Nutrition   .
Medical sciences.
Biomedical Research.
Molecular Genetics.
Humanities and Social Sciences.
Nutrition.
Health Sciences.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Forward
  • History of Retinoic Acid Receptors
  • Architecture of DNA Bound RAR Heterodimers
  • Retinoic Acid Receptors: Structural Basis for Coregulator Interaction and Exchange
  • Evolution of Retinoic Acid Receptors and Retinoic Acid Signaling
  • RXRs: Collegial Partners
  • Nuclear and Extra-Nuclear Effects of Retinoic Acid Receptors: How they are interconnected- The Roles of Retinoic Acid and Retinoic Acid Receptors in Inducing Epigenetic Changes
  • RARs and micro RNAs
  • Integrative genomics to dissect retinoids functions
  • Complexity of the RAR‐Mediated Transcriptional Regulatory Programs
  • Index.

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