The Essential Guide to N-of-1 Trials in Health

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N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial d...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Nikles, Jane (Editor ), Mitchell, Geoffrey (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Temas:
Medicine-Research.
Biology-Research.
Therapeutics.
Psychology.
Biometry.
Pharmacy.
Biomedical Research.
Behavioral Sciences and Psychology.
Biostatistics.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Preface
  • Introduction
  • What are N-of-1 trials?- N-of-1 trials in the behavioural sciences
  • N-of-1 trials in medical contexts
  • Aggregated N-of-1 trials
  • Methodological considerations for N-of-1 trials
  • Randomization, allocation concealment and blinding
  • Data collection and quality control
  • Individual reporting of N-of-1 trials to patients and clinicians
  • Assessing and reporting adverse events
  • Research ethics and N-of-1 trials
  • Statistical analysis of N-of-1 trials
  • The economics of N-of-1 trials
  • Reporting N-of-1 trials to professional audiences
  • Single patient open trials
  • Systematic review and meta-analysis using N-of-1 trials
  • Where are N-of-1 trials headed?- Index.

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