Cargando…

The Essential Guide to N-of-1 Trials in Health

N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial d...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Nikles, Jane (Editor ), Mitchell, Geoffrey (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Temas:
Acceso en línea:Texto Completo

MARC

LEADER 00000nam a22000005i 4500
001 978-94-017-7200-6
003 DE-He213
005 20220114235426.0
007 cr nn 008mamaa
008 151005s2015 ne | s |||| 0|eng d
020 |a 9789401772006  |9 978-94-017-7200-6 
024 7 |a 10.1007/978-94-017-7200-6  |2 doi 
050 4 |a R850.A1-854 
050 4 |a QH315-320 
072 7 |a MBGR  |2 bicssc 
072 7 |a MED000000  |2 bisacsh 
072 7 |a MBGR  |2 thema 
082 0 4 |a 610.72  |2 23 
245 1 4 |a The Essential Guide to N-of-1 Trials in Health  |h [electronic resource] /  |c edited by Jane Nikles, Geoffrey Mitchell. 
250 |a 1st ed. 2015. 
264 1 |a Dordrecht :  |b Springer Netherlands :  |b Imprint: Springer,  |c 2015. 
300 |a XI, 245 p. 31 illus., 17 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
505 0 |a Preface -- Introduction -- What are N-of-1 trials?- N-of-1 trials in the behavioural sciences -- N-of-1 trials in medical contexts -- Aggregated N-of-1 trials -- Methodological considerations for N-of-1 trials -- Randomization, allocation concealment and blinding -- Data collection and quality control -- Individual reporting of N-of-1 trials to patients and clinicians -- Assessing and reporting adverse events -- Research ethics and N-of-1 trials -- Statistical analysis of N-of-1 trials -- The economics of N-of-1 trials -- Reporting N-of-1 trials to professional audiences -- Single patient open trials -- Systematic review and meta-analysis using N-of-1 trials -- Where are N-of-1 trials headed?- Index. 
520 |a N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs.  They have the potential to revolutionize the way clinical medicine is practiced. Whether you are a busy clinician, a researcher or a student, this book provides everything you need to know about N-of-1 trials. Written and edited by some of the world's leading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more. Full of examples and well illustrated, it is a comprehensive compendium of issues surrounding the design, conduct, interpretation and implementation of N-of-1 trials in a health system. 
650 0 |a Medicine-Research. 
650 0 |a Biology-Research. 
650 0 |a Therapeutics. 
650 0 |a Psychology. 
650 0 |a Biometry. 
650 0 |a Pharmacy. 
650 1 4 |a Biomedical Research. 
650 2 4 |a Therapeutics. 
650 2 4 |a Behavioral Sciences and Psychology. 
650 2 4 |a Biostatistics. 
650 2 4 |a Pharmacy. 
700 1 |a Nikles, Jane.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
700 1 |a Mitchell, Geoffrey.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9789401771993 
776 0 8 |i Printed edition:  |z 9789401772013 
776 0 8 |i Printed edition:  |z 9789402404401 
856 4 0 |u https://doi.uam.elogim.com/10.1007/978-94-017-7200-6  |z Texto Completo 
912 |a ZDB-2-SBL 
912 |a ZDB-2-SXB 
950 |a Biomedical and Life Sciences (SpringerNature-11642) 
950 |a Biomedical and Life Sciences (R0) (SpringerNature-43708)