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Evolution-adjusted Tumor Pathophysiology: The Novel Language of Tumor Biology /

Combined modularized therapies for metastatic cancer are pointing to central problems of communication among 'systems participators'. A communication theory explains 'social engineering', endogenously induced or by implementing non-normative boundary conditions. Evolution-adjuste...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Reichle, Albrecht (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Preface.-I Introduction.-Communication ─ evolution ─ pathophysiology: An endogenous conjunction ─Instead of an introduction.-II Combined modularized therapies for metastatic tumors: Pointing to central problems of communication among 'systems participators' in tumors
  • Applied systems biology for the control of metastatic cancer: Therapeutic top-down strategy for targeting the tumors' normativity
  • Targeting the proangiogenic network in angiosarcomas: Biomodulatory therapy.- Long-term results of combined modularized, immune-modulatory, angiostatic, and antiinflammatory therapy in systemically pre-treated multi-systems Langerhans cell histiocytosis.- Redirecting and modulating rationalizations of tumor-immanent normative functions in castration-resistant prostate ancer.-III Social engineering: Biomodulation, either endogenously initiated or by implementation of non-normative boundary conditions
  • Non-hierarchically organized operations in malignancies: Stromal dysfunction induces hematopoetic malignancies.- Biomodulatory therapy approaches in renal clear cell carcinoma: A perspective.- Proteome analysis identified the PPARc ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction.IV   The tumors' normativity: Reconstructing and operationalizing starting  points for an evolution theory.- The philosophical quest of a cancer cell: Redefining existentialism.- The tumor's normativity: Normative structures, action norms and decision maxims as therapeutic targets for tumor therapy.- Criticizable claims for the validity of communication acts in biological systems: Therapeutic implications in cancer.-V Evolution theory.- Evolution theory: Its practical relevance for understanding tumor development and specifying tumor therapy
  • Modularity, subjectivity, intersubjectivity and normativity: Clinically applicable operative benchmarks
  • Turning upside down the mode of science to emphasize and harness the impact of environmental communicative events. VI   From genome- or organ-centric to rationalization-centric systematization of tumors
  • Purposive-rational tumor therapy: Exploiting the tumor's 'living world' for diversifying, specifying and personalizing tumor therapy
  • Including rationalizations of tumor-associated normative notions in pathophysiologic considerations: Communication-theoretical implications.-VII  Reconstruction of tumor-immanent normative functions, structures and decision maxims (hubs).- Bridging a diagnostic and therapeutic gap: Selecting, assessing and categorizing tumor-associated normative notions.- Personalizing tumor pathophysiology by diagnosing developmental problems in tumors with imaging techniques
  • Biologic memory: Induction by metronomically administered combined modularized therapy.- VIII The tool of rationalizations constituting tumor-associated normative notions: The non-genomic counterpart of the tumor genome and therefore, an important therapeutic target for diversifying palliative care
  • Diversifying and specifying palliative care for patients with metastatic cancer by therapeutic implementation of non-normative boundary conditions
  • Targeting a hallmark of cancer: Simultaneous inflammation and tumor control for palliative care in metastatic cancer.-IX  Novel clinical and pharmaceutical technology for bioengineering tumor response.- Combined modularized tumor therapy ─ tumor biology ─ and prognostic factors: Bioengineering tumor response.-X Objectifying the systems objects' subjectivity in biological systems: A novel reification of the scientific picture about the 'objective' world
  • The systems objects' subjectivity as scientific object. Index.