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Cytochrome P450 2E1: Its Role in Disease and Drug Metabolism

The book deals with various clinical aspects of cytochrome P450 2E1 (CYP2E1), which is a potent source for oxidative stress. Oxidative stress is critical for pathogenesis of diseases and CYP2E1 is a major contributor for oxidative stress. Several clinical disorders are associated with changes in reg...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Dey, Aparajita (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Colección:Subcellular Biochemistry, 67
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Cytochrome P450 2E1 and its clinical aspects
  • Nrf2 and antioxidant defense against CYP2E1 toxicity
  • The role of Cytochrome P-4502E1 in ethanol-mediated carcinogenesis
  • The Importance of CYP2E1 in the pathogenesis of alcoholic liver disease and drug toxicity and the role of the proteasome
  • Relevance of CYP2E1 to non-alcoholic fatty liver disease
  • CYP2E1-catalyzed alcohol metabolism
  • CYP2E1, oxidative stress, post-translational modifications and  lipid metabolism
  • The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system.