Phosphoinositides I: Enzymes of Synthesis and Degradation

Phosphoinositides play a major role in cellular signaling and membrane organization. During the last three decades we have learned that enzymes turning over phosphoinositides control vital physiological processes and are involved in the initiation and progression of cancer, inflammation, neurodegene...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Balla, Tamas (Editor ), Wymann, Matthias (Editor ), York, John D. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2012.
Edición:1st ed. 2012.
Colección:Subcellular Biochemistry, 58
Temas:
Medicine > Research.
Biology > Research.
Neurosciences.
Medical genetics.
Neurochemistry.
Biomedical Research.
Neuroscience.
Medical Genetics.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • 1. The Phosphatidylinositol 4-kinases: Don't Call it a Comeback
  • 2. PIP kinases from the cell membrane to the nucleus
  • 3. The Phospholipase C Isozymes and Their Regulation.- 4. Phosphoinositide 3-Kinases - A Historical Perspective
  • 5. PI 3-kinases - drug targets in inflammation and cancer
  • 6. Phosphoinositide 3-kinases in health and disease
  • 7. Phosphoinositide phosphatases: just as important as the kinases
  • 8. The PTEN and myobubularin phosphoinositide 3-phosphatases: linking lipid signalling to human disease.

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