Advances in Mitochondrial Medicine

Mitochondria are far more than the "powerhouse" of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Scatena, Roberto (Editor ), Bottoni, Patrizia (Editor ), Giardina, Bruno (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2012.
Edición:1st ed. 2012.
Colección:Advances in Experimental Medicine and Biology, 942
Temas:
Medicine-Research.
Biology-Research.
Cancer.
Pharmacology.
Clinical biochemistry.
Biomedical Research.
Cancer Biology.
Medical Biochemistry.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Section I - Physiology and structure of Mitochondria
  • 1.               The oxidative phosphorylation system in mammalian mitochondria
  • 2. Physiology and pathophysiology of mitochondrial DNA
  • 3. Mitochondrial calcium as a key regulator of mitochondrial activities
  • 4. Mitochondria and Nitric Oxide: Chemistry and Pathophysiology
  • 5. Mitochondria and reactive oxygen species - which role in physiology and pathophysiology?
  • 6. Uncoupling proteins: molecular, functional, regulatory, physiological and pathological aspects
  • 7. The mitochondrial pathways of apoptosis
  • Section II - Mitochondria and disease
  • 8. Inherited mitochondrial disorders
  • 9. Mitochondria and metabolism diseases
  • 10. Mitochondria and diabetes. An intriguing pathogenetic role
  • 11. Mitochondria and heart diseases
  • 12. Mitochondria in neurodegeneration
  • 13. Mitochondria and cancer: a growing role in apoptosis, cancer cell metabolism and dedifferentiation
  • Section III - Mitochondria and Aging
  • 14.Mitochondria and aging
  • 15. Mitochondria and pharmacology. -16. Iatrogenic mitochondriopathies: a recent lesson from nucleoside/nucleotide reverse transcriptase inhibitors
  • 17. Dysfunction of mitochondrial respiratory chain complex I in neurological disorders: genetics and pathogenetic mechanisms
  • 18. Anthracyclines and mitochondria
  • Section IV-  Applications of Mitochondrial science
  • 19. Mitochondrial proteomics approaches for new potential diagnostic and prognostic biomarkers in cancer
  • 20. Mitochondria in Anthropology and forensic medicine.  .

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