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Systems Biology in Biotech & Pharma A Changing Paradigm /

Systems Biology (SB) is a suite of technologies and methodologies that resulted, conceptually from the merging of two basic paradigms, reductionism and holism. It represents a combination of reductionist and holistic approaches to the relationships among the elements of a system, with the goal of id...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores principales: Prokop, Aleš (Autor), Michelson, Seth (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2012.
Edición:1st ed. 2012.
Colección:SpringerBriefs in Pharmaceutical Science & Drug Development,
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Abstract
  • 1 Introduction: Discovery & Development - New Facet Of Industry, New Tools And Lead Optimization: 1.1 Scope And Content Of This Review
  • 2 Discovery: Use Of Systems Biology For Identifying Targets
  • 3 Integrative Systems Biology I - Biochemistry:  Phase I Lead Discovery & Molecular Interactions
  • 4 Integrative Systems Biology Ii - Molecular Biology:  Phase 2 Lead Discovery & In Silico Screening
  • 5. Discovery: Computational Systems Biology (Csb) In Health & And Disease I
  • 6 Development:  In Vivo Pharmacology - Systems Biology In Health & Disease Ii
  • 7 Development: Pharmacokinetics - Systems Biology In Health & Disease Iii
  • 8 Development:  Multiscale Csb - Simulation Tools
  • 9 Development:  Drug Formulation & Delivery
  • 10 Development: Preclinical Model Based Drug Development
  • 11 Systems Biology: Impact On Pharma And Biotech
  • 12 Acknowledgment
  • 13 Bibliography.