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Systems Biology in Biotech & Pharma A Changing Paradigm /
Systems Biology (SB) is a suite of technologies and methodologies that resulted, conceptually from the merging of two basic paradigms, reductionism and holism. It represents a combination of reductionist and holistic approaches to the relationships among the elements of a system, with the goal of id...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores principales: | , |
| Autor Corporativo: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Dordrecht :
Springer Netherlands : Imprint: Springer,
2012.
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| Edición: | 1st ed. 2012. |
| Colección: | SpringerBriefs in Pharmaceutical Science & Drug Development,
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| Temas: | |
| Acceso en línea: | Texto Completo |
MARC
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| 001 | 978-94-007-2849-3 | ||
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| 100 | 1 | |a Prokop, Aleš. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 245 | 1 | 0 | |a Systems Biology in Biotech & Pharma |h [electronic resource] : |b A Changing Paradigm / |c by Aleš Prokop, Seth Michelson. |
| 250 | |a 1st ed. 2012. | ||
| 264 | 1 | |a Dordrecht : |b Springer Netherlands : |b Imprint: Springer, |c 2012. | |
| 300 | |a XVIII, 127 p. 16 illus. in color. |b online resource. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
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| 490 | 1 | |a SpringerBriefs in Pharmaceutical Science & Drug Development, |x 1864-8126 | |
| 505 | 0 | |a Abstract -- 1 Introduction: Discovery & Development - New Facet Of Industry, New Tools And Lead Optimization: 1.1 Scope And Content Of This Review -- 2 Discovery: Use Of Systems Biology For Identifying Targets -- 3 Integrative Systems Biology I - Biochemistry: Phase I Lead Discovery & Molecular Interactions -- 4 Integrative Systems Biology Ii - Molecular Biology: Phase 2 Lead Discovery & In Silico Screening -- 5. Discovery: Computational Systems Biology (Csb) In Health & And Disease I -- 6 Development: In Vivo Pharmacology - Systems Biology In Health & Disease Ii -- 7 Development: Pharmacokinetics - Systems Biology In Health & Disease Iii -- 8 Development: Multiscale Csb - Simulation Tools -- 9 Development: Drug Formulation & Delivery -- 10 Development: Preclinical Model Based Drug Development -- 11 Systems Biology: Impact On Pharma And Biotech -- 12 Acknowledgment -- 13 Bibliography. | |
| 520 | |a Systems Biology (SB) is a suite of technologies and methodologies that resulted, conceptually from the merging of two basic paradigms, reductionism and holism. It represents a combination of reductionist and holistic approaches to the relationships among the elements of a system, with the goal of identifying its emergent properties and defining, quantitatively, molecular, cellular, tissue, organ and whole body processes. One manifestation of SB is as a tool for hypothesis generation about a system that is typically too large and complex to understand by simple reasoning. | ||
| 650 | 0 | |a Medicine-Research. | |
| 650 | 0 | |a Biology-Research. | |
| 650 | 0 | |a Biotechnology. | |
| 650 | 0 | |a Industrial microbiology. | |
| 650 | 0 | |a Pharmaceutical chemistry. | |
| 650 | 1 | 4 | |a Biomedical Research. |
| 650 | 2 | 4 | |a Biotechnology. |
| 650 | 2 | 4 | |a Industrial Microbiology. |
| 650 | 2 | 4 | |a Pharmaceutics. |
| 700 | 1 | |a Michelson, Seth. |e author. |4 aut |4 http://id.loc.gov/vocabulary/relators/aut | |
| 710 | 2 | |a SpringerLink (Online service) | |
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