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Cancer Systems Biology, Bioinformatics and Medicine Research and Clinical Applications /

This teaching monograph on systems approaches to cancer research and clinical applications provides a unique synthesis, by world-class scientists and doctors, of laboratory, computational, and clinical methods, thereby establishing the foundations for major advances not possible with current methods...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Cesario, Alfredo (Editor ), Marcus, Frederick (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2011.
Edición:1st ed. 2011.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • PART I - Introduction and background
  • 1. Introduction to systems approaches to cancer
  • 2. Cancer: clinical background and key challenges
  • PART II - Laboratory, clinical, data and educational resources
  • 3. Global molecular and cellular measurement technologies
  • 4. Cell lines, tissue samples, model organisms, biobanks
  • 5. Expression and genetic variation databases for cancer research
  • 6. Education and Research Infrastructures
  • PART III - Bioinformatics and systems biology analysis
  • 7. Mathematical tools in cancer signalling systems biology
  • 8. Computational tools for systems biology
  • 9. The hallmarks of cancer revisited through systems biology and network modeling
  • 10. Systems biology analysis of cell death pathways in cancer: how collaborative and interdisciplinary research helps
  • 11. Systems biology, bioinformatics and medicine approaches to cancer progression outcomes
  • 12. System dynamics at the physiological and tumour level
  • PART IV - Diagnosis, clinical and treatment applications
  • 13. Diagnostic and prognostic cancer biomarkers: from traditional to systems approaches
  • 14. Systems biology approaches to cancer drug development
  • 15. Circadian rhythms and cancer chronotherapeutics
  • 16. Clinical applications of systems approaches
  • 17. Cancer robustness and therapy strategies
  • PART V - Perspectives and conclusions
  • 18. Synthetic biology and perspectives
  • 19. Conclusions
  • Index.