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Antibody Expression and Production
Engineered antibodies currently represent over 30% of biopharmaceuticals in clinical trials and their total worldwide sales continue to increase significantly. The importance of antibody applications is reflected in their increasing clinical and industrial applications as well as in the progression...
| Clasificación: | Libro Electrónico |
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| Autor Corporativo: | |
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Dordrecht :
Springer Netherlands : Imprint: Springer,
2011.
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| Edición: | 1st ed. 2011. |
| Colección: | Cell Engineering ;
7 |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- 1 Expression of antibody in mammalian cells, Thomas Jostock
- 2 Bioreactor systems for producing antibody from mammalian cells, Darrin Kuystermans and Mohamed Al-Rubeai
- 3 Production of antibody in insect cells, Hideki Yamaji
- 4 Production of monoclonal antibodies in glycoengineered Pichia pastoris, Dongxing Zhu, Thomas Linden and Thomas Potgieter
- 5 Production of antibodies in Hansenula polymorpha, Georg Melmer, Stephan Hellwig, Grit Hehmann and Ulrike Dahlems
- 6 Expression of antibody in transgenic avians, Yoshinori Kawabe and Masamichi Kamihira
- 7 Production of antibodies in plants, Alejandro Sarrion-Perdigones, Paloma Juarez, Antonio Granell and Diego Orzaez
- 8 Production of antibody fab fragments in Escherichia coli, Hiroshi Tachibana and Masataka Takekoshi
- 9 Intrabody expression in mammalian cells, Silvia Biocca
- 10 Engineering of antibodies for cancer therapy, Lisa E. Goldsmith and Matthew K. Robinson
- 11 Recombinant bispecific antibodies for cancer therapy, Dafne Muller and Roland Kontermann
- 12 The role of glycosylation in therapeutic antibodies, Maureen Spearman, Ben Dionne and Mike Butler
- 13 Quality issues arising from post-translational modification of recombinant antibodies, Raymond Tyther and Nigel Jenkins
- 14 Purification of antibody, XueJun Han, Arther Hewig and Ganesh Vedantham
- Index.