CCN proteins in health and disease An overview of the Fifth International Workshop on the CCN family of genes /

The CCN family of genes currently comprises six secreted proteins (designated CCN16 i.e., Cyr61/CCN1; ctgf/CCN2; Nov/CCN3; WISP1/CCN4; WISP2/CCN5, and WISP3/CCN6) showing a strikingly conserved primary structure, with four modules sharing partial identity with IGF binding proteins, Von Willebrand pr...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Perbal, Annick (Editor ), Takigawa, Masaharu (Editor ), Perbal, Bernard (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands : Imprint: Springer, 2010.
Edición:1st ed. 2010.
Temas:
Medicine-Research.
Biology-Research.
Medical genetics.
Proteins .
Cytology.
Biomedical Research.
Medical Genetics.
Protein Biochemistry.
Cell Biology.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • A Recent Breakthrough in the CCN Field: Functional Interactions Between CCN2 and CCN3 are Uncovered
  • Report on the Fifth International Workshop on the CCN Family of Genes
  • Asking the Right Questions: What Can the Structure of the CCN Protein Domains Tell Us?
  • Nucleophosmin/B23: A Multifunctional Regulator that Determines the Fate of CCN2 mRNA
  • The CCN Genes as the "Master" Regulators of Angiogenesis, Vasculogenesis, Fibrogenesis and Cell Differentiation/Fate Specification in Mechanical Force-Driven Developmental Processes and Pathological Events
  • A Monoclonal Antibody Approach to CCN5 Domain Analysis
  • Matricellular Protein CCN2 Produced by Tubular Epithelial Cells Plays a Pivotal Role in Renal Fibrogenesis
  • Cooperative Regulation of Cell Proliferation and Differentiation by CCN2 and CCN3
  • The Role of CCN3 in Mesenchymal Stem Cells
  • Role of Connective Tissue Growth Factor in Cardiac Fibrosis
  • Gene Expression of CCN Family Members in Young and Aged Human Skin In Vivo
  • Global Expression Profiling Reveals a Role for CTGF/CCN2 in Lactogenic Differentiation of Mouse Mammary Epithelial Cells
  • CCN3 (NOV): A Negative Regulator of CCN2 (CTGF) Activity and an Endogenous Inhibitor of Fibrosis in Experimental Diabetic Nephropathy
  • Inhibitors of Connective Tissue Growth Factor (CCN2)-Mediated Fibrogenesis: Underlying Mechanisms and Prospects for Anti-fibrotic Therapy
  • CCN3 Promotes Melanoma Progression by Regulating Integrin Expression, Adhesion and Apoptosis Induced by Cytotoxic Drugs
  • CCN3: A NOVel Growth Factor in Leukaemia
  • Prognostic Relevance of CCN3 in Bone Sarcomas
  • CCN6 Regulates Breast Cancer Growth and Invasion Through Modulation of IGF Signaling and Epithelial to Mesenchymal Transition
  • Novel Transcriptional Regulation of CCN2/CTGF by Nuclear Translocation of MMP3.

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