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Pancreatic Beta Cell in Health and Disease

The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin, a key metabolic hormone, which plays a central role in the maintenance of glucose homeostasis regulating glucose uptake in muscle and adipose tissue as well as carbohydrate, fat, an...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Seino, Susumu (Editor ), Bell, Graeme I. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Tokyo : Springer Japan : Imprint: Springer, 2008.
Edición:1st ed. 2008.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Pancreatic Beta Cell and Insulin Biosynthesis
  • Architecture of Pancreatic Islets
  • Transcriptional Regulation of Insulin Gene Expression
  • The Biosynthesis of Insulin
  • Cell Signaling and Insulin Secretion
  • Metabolic Regulation of Insulin Secretion
  • Mechanisms of Beta-Cell Death in Diabetes
  • Ion Channels and Insulin Secretion
  • Gap Junctions and Insulin Secretion
  • Protein Kinase A-Independent Mechanism of cAMP in Insulin Secretion
  • Regulation of Insulin Granule Exocytosis
  • Mechanism of Insulin Exocytosis Analyzed by Imaging Techniques
  • Two-Photon Excitation Imaging of Insulin Exocytosis
  • Pancreatic Development and Beta-Cell Formation
  • Regulation of Beta-Cell Growth and Death
  • Beta-Cell Replication
  • Stem Cells as a Cure for Diabetes
  • Use of Extra-Pancreatic Tissues for Cell Replacement Therapy for Diabetes
  • Incretins and Beta-Cell Function
  • Molecular Biology of Gluco-Incretin Function
  • Incretins and Regulation of Insulin Secretion
  • Pancreatic Beta Cell and Disease
  • Pancreatic Islet Pathology in Type 2 Diabetes
  • Genetic Disorders of the Pancreatic Beta Cell and Diabetes (Permanent Neonatal Diabetes and Maturity-Onset Diabetes of the Young)
  • ATP-Sensitive Potassium Channels in Health and Disease
  • Glucokinase in Glucose Homeostasis, Diabetes Mellitus, Hypoglycemia, and as Drug Receptor.