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C-Type Lectin Receptors in Immunity

The book presents the latest findings on C-type lectin receptors, focusing on individual receptors and their signaling. In recent years there have been great advances in the understanding of the function of these receptors as a newly emerging family of pattern-recognition receptors (PRRs) for pathog...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Yamasaki, Sho (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Tokyo : Springer Japan : Imprint: Springer, 2016.
Edición:1st ed. 2016.
Temas:
Acceso en línea:Texto Completo

MARC

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245 1 0 |a C-Type Lectin Receptors in Immunity  |h [electronic resource] /  |c edited by Sho Yamasaki. 
250 |a 1st ed. 2016. 
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300 |a VI, 215 p. 29 illus., 6 illus. in color.  |b online resource. 
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505 0 |a Part 1 ITAM-coupled Activating Receptors -- 1 Dectin-2 in anti-microbial immunity and homeostasis -- 2 The function of Mincle as a danger sensor -- 3 The DAP12-Associated Myeloid C-type Lectin 5A (CLEC5A) -- Part 2 HemITAM-bearing Receptors -- 4 Dectin-1 (CLEC7A, BGR, CLECSF12) -- 5 DNGR-1, an F-actin-binding C-type lectin receptor involved in cross-presentation of dead cell-associated antigens by dendritic cells -- 6 C-type lectin-like receptor 2 (CLEC-2) -- Part 3 ITIM-bearing Receptors -- 7 Dendritic cell immunoreceptor (DCIR): An ITIM-harboring C-type lectin receptor -- 8 Regulation and Function of the Inhibitory C-type Lectin Clec12A/MICL -- Part 4 Other receptors and related topics -- 9 DC-SIGN in infection and immunity -- 10 LOX-1 and immunity -- 11 MGL/CD301 as a unique C-type lectin expressed on dendritic cells and macrophages -- 12 Structural aspects of C-type lectin receptors -- 13 The Ligands of C-Type Lectins. 
520 |a The book presents the latest findings on C-type lectin receptors, focusing on individual receptors and their signaling. In recent years there have been great advances in the understanding of the function of these receptors as a newly emerging family of pattern-recognition receptors (PRRs) for pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Comprising four parts: ITAM-coupled Activating Receptors; HemITAM-bearing Receptors; ITIM-bearing Receptors; and Other Receptors and Related Topics, this comprehensive review covers a broad range of C-type lectin receptors. The updated information on C-type lectin receptors and their ligands provided will appeal to a wide readership, from basic immunologists to physicians and surgeons. In addition, sections on novel drug development make this a valuable resource for pharmaceutical scientists. 
650 0 |a Immunology. 
650 0 |a Biochemistry. 
650 0 |a Pharmaceutical chemistry. 
650 1 4 |a Immunology. 
650 2 4 |a Biochemistry. 
650 2 4 |a Pharmaceutics. 
700 1 |a Yamasaki, Sho.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
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