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Neurodegenerative Disorders as Systemic Diseases

This book sheds new light on neurodegenerative disorders as systemic diseases. Classically, neuronal cell death was a hallmark of such disorders. However, it has become evident that neural dysfunction is more important in the pathophysiology of neurodegenerative disorders. More recently, the prionoi...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Wada, Keiji (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Tokyo : Springer Japan : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • PART I A NEW CONCEPT OF NEURODEGENERATION IN BIOLOGY AND PATHOPHYSIOLOGY
  • 1 Conformational disease and RNA disease theory in the context of neurodegenerative diseases
  • 2 Brain-peripheral organ communication
  • 3 The brain-immune network in spinal cord injury
  • PART II CHANGES IN CLINICAL EVALUATION AND NEW BIOMARKERS
  • 4 Renovation of clinical evaluation and new biomarkers
  • 5 Clinical Systems Neuroscience
  • PART III RISK FACTORS IN NEURODEGENERATION
  • 6 Genetic risk factors for neurodegenerative diseases
  • 7 Intermediate phenotypes approach for neuropsychiatric disorders
  • PART IV FUTURE DIRECTIONS FOR THERAPY
  • 8 Significance of mechanism-oriented research toward neuronal protection therapy against neurodegenerative disorders ~ ZNRF1 E3 ubiquitin ligase as a critical mediator for Wallerian degeneration and neuronal apoptosis
  • 9 Drug development for neurodegenerative diseases
  • 10 Physical therapy and rehabilitation in patients with degenerative cerebellar diseases: current evidence and future direction
  • 11 Home- and Community-based medical care for neurodegenerative diseases -ALS as an illustration-
  • PART V HEALTH PROMOTION: PREVENTION AND QUALITY OF LIFE
  • 12 Information Environment and Brain Function: A New Concept of the Environment for the Brain
  • 13 Social Implementation of Neurodegenerative Disease Research and Neuroethics.-.