Cargando…

Behçet's Disease From Genetics to Therapies /

This book, besides reviewing basic and clinical aspects of Behçet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of Behçet's disease is still unknown, it is well known that genetic factors, such as HLA-B51...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Ishigatsubo, Yoshiaki (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Tokyo : Springer Japan : Imprint: Springer, 2015.
Edición:1st ed. 2015.
Temas:
Acceso en línea:Texto Completo

MARC

LEADER 00000nam a22000005i 4500
001 978-4-431-54487-6
003 DE-He213
005 20220117012534.0
007 cr nn 008mamaa
008 141203s2015 ja | s |||| 0|eng d
020 |a 9784431544876  |9 978-4-431-54487-6 
024 7 |a 10.1007/978-4-431-54487-6  |2 doi 
050 4 |a RC927-927.5 
072 7 |a MJM  |2 bicssc 
072 7 |a MED083000  |2 bisacsh 
072 7 |a MJM  |2 thema 
082 0 4 |a 616.723  |2 23 
245 1 0 |a Behçet's Disease  |h [electronic resource] :  |b From Genetics to Therapies /  |c edited by Yoshiaki Ishigatsubo. 
250 |a 1st ed. 2015. 
264 1 |a Tokyo :  |b Springer Japan :  |b Imprint: Springer,  |c 2015. 
300 |a IX, 176 p. 38 illus., 31 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
505 0 |a 1. Overview -- 2. The Immunopathology of Behcet's Disease -- 3. Genetics -- 4. Ocular Involvement -- 5. Vascular Involvement of Behçet's Disease -- 6. Neurological Involvement -- 7. Gastrointestinal Involvement -- 8. Mucocutaneous Manifestations -- 9. Perspective . 
520 |a This book, besides reviewing basic and clinical aspects of Behçet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of Behçet's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- Behçet's disease. Behçet's Disease:  From Genetics to Therapies  provides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in Behçet's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons. 
650 0 |a Rheumatology. 
650 0 |a Allergy. 
650 0 |a Dermatology. 
650 0 |a Ophthalmology. 
650 0 |a Gastroenterology. 
650 1 4 |a Rheumatology. 
650 2 4 |a Allergology. 
650 2 4 |a Dermatology. 
650 2 4 |a Ophthalmology. 
650 2 4 |a Gastroenterology. 
700 1 |a Ishigatsubo, Yoshiaki.  |e editor.  |4 edt  |4 http://id.loc.gov/vocabulary/relators/edt 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer Nature eBook 
776 0 8 |i Printed edition:  |z 9784431544869 
776 0 8 |i Printed edition:  |z 9784431544883 
776 0 8 |i Printed edition:  |z 9784431561705 
856 4 0 |u https://doi.uam.elogim.com/10.1007/978-4-431-54487-6  |z Texto Completo 
912 |a ZDB-2-SME 
912 |a ZDB-2-SXM 
950 |a Medicine (SpringerNature-11650) 
950 |a Medicine (R0) (SpringerNature-43714)