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Development of Novel Anti-HIV Pyrimidobenzothiazine Derivatives

The author successfully developed novel anti-HIV PD 404182 derivatives that exhibited submicromolar inhibitory activity against both HIV-1 and HIV-2. His thesis is in three parts. The first part expounds efficient methods for the synthesis of tricyclic heterocycles related to PD 404182 based on the...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Mizuhara, Tsukasa (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Tokyo : Springer Japan : Imprint: Springer, 2013.
Edición:1st ed. 2013.
Colección:Springer Theses, Recognizing Outstanding Ph.D. Research,
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Introduction
  • Development of Divergent Synthetic Methods of Pyrimidobenzothiazine and Related Tricyclic Heterocycles
  • Structure-Activity Relationship Study of PD 404182 Derivatives for the Highly Potent Anti-HIV Agents.- Design and Synthesis of Photoaffinity Probes and Their Application to Target Identification Study of PD 404182
  • Conclusion.