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TGF-β in Human Disease
Transforming growth factor-β (TGF-β) is a secreted polypeptide with multifunctional properties manifested during embryonic development, adult organ physiology, and pathobiology of major diseases, including cancer and fibrotic and cardiovascular diseases. The signaling pathway of TGF-β now is rather...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor Corporativo: | |
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Tokyo :
Springer Japan : Imprint: Springer,
2013.
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| Edición: | 1st ed. 2013. |
| Temas: | |
| Acceso en línea: | Texto Completo |
Tabla de Contenidos:
- Part I Introduction
- 1 Transforming Growth Factor-β Signaling
- 2 TGF-β Signaling in Stem Cell Fate Determination
- 3 Emerging Roles of TGF-β Co-receptors in Human Disease
- Part II Cancer, Fibrosis, and Inflammation
- 4 TGF-β in Cancer Stem Cells
- 5 TGF-β as Tumor Suppressor: In Vitro Mechanistic Aspects of Growth Inhibition
- 6 TGF-β as Tumor Suppressor: Lessons from Mouse Models
- 7 The Multifunctional Roles of TGF-β in Navigating the Metastatic Cascade
- 8 TGF-β Signaling in Leukemogenesis
- 9 TGF-β in Skin Cancer and Fibrosis
- 10 The Role of TGF-β in Cutaneous Melanoma Biology
- 11 The Transforming Growth Factor-Beta (TGF-β) in Liver Fibrosis
- 12 TGF-β and Inhibitory Smads in Inflammation
- Part III Cardiovascular Diseases
- 13 TGF-β and Cardiovascular Disorders
- 14 TGF-β Signaling in Physiological and Pathological Angiogenesis
- 15 TGF-β Signaling Pathway and MicroRNAs in Cardiovascular Disease
- Part IV Other Diseases
- 16 TGF-β and Genetic Skeletal Diseases
- 17 TGF-β in Brain Disorders
- 18 TGF-β and Metabolic Homeostasis
- Part V Disease Prognosis and Therapy. 19 Targeting Pro-Angiogenic TGF-β Signaling in the Tumor Microenvironment.