Non-viral Gene Therapy Gene Design and Delivery /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Taira, Kazunari (Editor ), Kataoka, Kazunori (Editor ), Niidome, Takuro (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Tokyo : Springer Japan : Imprint: Springer, 2005.
Edición:1st ed. 2005.
Temas:
Cytology.
Biotechnology.
Medicine-Research.
Biology-Research.
Clinical biochemistry.
Cell Biology.
Biomedical Research.
Chemical Bioengineering.
Medical Biochemistry.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Molecules for Gene Therapy
  • Recent Progress in Non-viral Gene Delivery
  • Physical Chemistry of DNA-Carrier Complexes
  • Liposomes
  • Polymeric Gene Carriers
  • Development of a Supramolecular Nanocarrier for Gene Delivery Based on Cationic Block Copolymers
  • Chitosan
  • Dendrimers as DNA Carriers
  • Use of Synthetic Peptides for Non-viral Gene Delivery
  • An Oligonucleotide Carrier Based on ?-1,3-Glucans
  • Biological and Chemical Hybrid Vectors
  • Controlled Gene Delivery
  • Pharmacokinetics of Gene Delivery in Cells
  • Active DNA Release from Complexes
  • Controlled Release of DNA Using Thermoresponsive Polymers
  • Active Transport of Exogenous Genes into the Nucleus
  • Controlled Intracellular Localization of Oligonucleotides by Chemical Conjugation
  • Functional Nucleotide Sequences Capable of Promoting Non-viral Genetic Transfer
  • Shielding of Cationic Charge of the DNA Complex to Avoid Nonspecific Interactions for In Vivo Gene Delivery
  • In Vivo Gene Transfer by Ligand-Modified Gene Carriers
  • Optimizing Polyplexes into Synthetic Viruses for Tumor-Targeted Gene Therapy
  • Gene Transfer and Target Diseases
  • Clinical Trials Using Non-viral Gene Delivery Systems
  • Current Protocols of Gene Delivery
  • Evaluation of Size and Zeta Potential of DNA/Carrier Complexes
  • Observation of DNA/Carrier Complexes Under Fluorescence Microscopy
  • Synthesis of Chemically Modified Chitosan and a Study of Its Gene Transfection Efficiency
  • Newly Designed DNA Fragments for Gene Correction
  • Evaluation of Gene Expression In Vivo After Intravenous and Intraportal Administration of Lipoplexes
  • Evaluation by Southern Blot Hybridization of DNA Administered with a Gene Carrier to Organs
  • Evaluation of the Immune Response After Administration of Plasmid DNA-Non-viral Vector Complexes
  • Gateway RNAi
  • Design of Genes Based on Current RNA Technology
  • Design of Intracellularly Active Ribozymes and siRNAs
  • RNAi-Based Inhibition Specific for Mutant Alleles in Autosomal Dominant Diseases: Sequence-Dependent and -Independent Discrimination of Mutant and Wild-Type Alleles by siRNA
  • In Vivo RNA Interference: Another Tool in the Box?
  • Suppression of Gene Expression via Chromatin Remodeling and the siRNA-Induced Silencing of Transcription
  • Intracellular Delivery of Nucleic Acids: Differences Between Transfection and siFection Reflect Differences Between DNA and RNA, and Between Oligodeoxynucleotides and Oligonucleotides
  • In Vivo Antitumor Activity of a New Cationic Liposome siRNA Complex
  • Enhancing RNAi with Synthetic RNA Duplexes.

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