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Erythropoietins, Erythropoietic Factors, and Erythropoiesis Molecular, Cellular, Preclinical, and Clinical Biology /

This second edition is a one-source guide to current information about red blood cell physiology and the action of native and recombinant human erythropoietic factors. Topics in the fields of erythropoiesis, recombinant protein discovery and production, and treatment of patients with anemia due to r...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Elliott, Steven G. (Editor ), Foote, MaryAnn (Editor ), Molineux, Graham (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2009.
Edición:2nd ed. 2009.
Colección:Milestones in Drug Therapy,
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Background
  • Erythropoiesis: an overview
  • Regulation of endogenous erythropoietin production
  • Biology of erythropoietin
  • Erythropoiesis-genetic abnormalities
  • Erythropoiesis-stimulating agents
  • Studies of erythropoiesis and the discovery and cloning of recombinant human erythropoietin
  • Commercial production of recombinant erythropoietins
  • Biosimilar epoetins
  • New molecules and formulations
  • Erythropoietin receptor
  • Structural basis for the signal transduction of erythropoietin
  • Intracellular signaling by the erythropoietin receptor
  • Mechanism of erythropoietin receptor activation
  • Clinical utility
  • Pharmacokinetics of erythropoiesis-stimulating agents
  • Use of erythropoietic stimulating agents in the setting of renal disease
  • Abuse of recombinant erythropoietins and blood products by athletes
  • Role and regulation of iron metabolism in erythropoiesis and disease
  • Nonhematopoietic effects of erythropoiesis-stimulating agents.