The Network Collective Rise and Fall of a Scientific Paradigm /

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The network paradigm dominated immunological research from the early 1970s to the late 1980s. The originator, Niels Jerne, hypothesized that the vast diversity of antibodies in each individual forms a network of mutual "idiotypic" recognition, thus regulating the immune system. In context...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Eichmann, Klaus (Autor)
Autor Corporativo: SpringerLink (Online service)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2008.
Edición:1st ed. 2008.
Temas:
Life sciences.
Life Sciences.
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Autobiographical note
  • Autobiographical note
  • Scientific Knowledge, Delusive or Deductive
  • Realism, constructivism, and the naiveté of the experimental scientist
  • Beyond underdeterminism: Popper, Kuhn, et al.
  • The anthropology of science: Ludwik Fleck et al.
  • The science wars
  • Origins, Rise, and Fall of the Network Paradigm
  • The immune system, pre-network paradigms
  • The necessity for an interactive theory of immunity
  • Proto-ideas of the network theory: antibody self-regulation, idiotypy, the brain analogy, and cybernetics
  • The idiotypic network theory
  • The T cell receptor puzzle
  • Suppression turned idiotypic
  • Network mannerism
  • Post-network immunology: Idiotypic network continues at the bedside
  • Hindsight
  • Science between Fact and Fiction
  • The fictional nature of scientific notions
  • Fiction turned fact: The case of antibodies
  • The enticing network: Fiction forever
  • Logic and laws in life science.

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