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Molecular, Clinical and Environmental Toxicology Volume 1: Molecular Toxicology /

Molecular Toxicology is the first volume of a three-volume set Molecular, Clinical and Environmental Toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals in daily life. By providing intriguing insights far down to the molecular level, t...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: SpringerLink (Online service)
Otros Autores: Luch, Andreas (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Basel : Birkhäuser Basel : Imprint: Birkhäuser, 2009.
Edición:1st ed. 2009.
Colección:Experientia Supplementum, 99
Temas:
Acceso en línea:Texto Completo
Tabla de Contenidos:
  • Historical milestones and discoveries that shaped the toxicology sciences
  • Physiologically based toxicokinetic models and their application in human exposure and internal dose assessment
  • The role of biotransformation and bioactivation in toxicity
  • Genotoxicity: damage to DNA and its consequences
  • Role of DNA repair in the protection against genotoxic stress
  • On the impact of the molecule structure in chemical carcinogenesis
  • Chemical induced alterations in p53 signaling
  • Molecular pathways involved in cell death after chemically induced DNA damage
  • The aryl hydrocarbon receptor at the crossroads of multiple signaling pathways
  • Mapping the epigenome - impact for toxicology
  • Receptors mediating toxicity and their involvement in endocrine disruption
  • Toxicogenomics: transcription profiling for toxicology assessment
  • The role of toxicoproteomics in assessing organ specific toxicity
  • High-throughput screening for analysis of in vitro toxicity.